Informatics

Application note: Real-time detection of Gs and Gi Signalling in living cells

20 June 2018 | By BMG Labtech GmbH

Genetically-encoded biosensors from Montana Molecular allow for detection of GPCR signalling...

Expert view: Rising growth of the global high‑content screening software and services market

11 June 2018 | By Jeff McMillan (Senior Product Manager Imaging at Molecular Devices)

The global high-content screening (HCS) software and services market accounted for over $500 million in 2017 and is expected to reach approximately $1.4 billion by 2026, increasing at a compound annual growth rate of more than 11%, says Jeff McMillan, Senior Product Manager Imaging, Molecular Devices.

Transforming translational research: CANscript^TM – a better predictive model for oncology

8 June 2018 | By Mark Paris

This webinar focused on a recent study evaluating a cohort of head and neck squamous cell carcinoma (HNSCC) patient tumours treated with anti-PD1 using CANscript™.

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Tau mutations may increase cancer risk

25 May 2018 | By Dr Zara Kassam (Drug Target Review)

Mutations in the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer...

Scientists reveal model that estimates lifetime risk of developing Alzheimer’s dementia

23 May 2018 | By Drug Target Review

The Alzheimer’s Association have published a study wherein a model estimates the lifetime risk of an individual developing Alzheimer’s disease dementia. The risk varies with such factors as age and gender, and crucially takes account of preclinical biological changes.

Lab-on-a-chip device mimics eye damage due to intense light

11 May 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers create eye neuron network model to study retinal diseases, possible treatment options...

ELRIG UK hosts inaugural Discovery Technologies event

8 May 2018 | By ELRIG

ELRIG (European Laboratory Research & Innovation Group) has announced its first Discovery Technologies meeting, which will take place at Alderley Park, located near Macclesfield in Cheshire.

Whitepaper: Smart cell monitoring

3 May 2018 | By Del Trezise, Essen BioScience

This whitepaper outlines how advances in real-time live-cell monitoring and analysis methods are addressing these changing needs.

Transforming translational research: CANscript^TM – A better predictive model for oncology

27 April 2018 | By Mitra Biotech

In this webinar, speaker Mark Paris, PhD discussed a recent study evaluating a cohort of HNSCC patient tumours treated with anti-PD1 using CANscript TM;. He also be reviewed the results of this study as a means of investigating predictors of clinical response and identifying mechanisms of resistance.

Biomarker endpoints for Parkinson’s disease

26 April 2018 | By Charles River Laboratories

This webinar provides a comprehensive review of the validation data from established and novel animal models of Parkinson’s disease.

in vitro phenotypic assays for Parkinson’s disease

26 April 2018 | By Charles River Laboratories

This webinar highlights cell based assays for Parkinson’s disease that include endpoints such as a-synuclein aggregation and mitophagy readouts.

The European Life Sciences Community meets at BASEL LIFE

13 April 2018 | By BASEL Life Science

Leading experts of the European Life Sciences Community are engaging under the name BASEL LIFE to establish a bridge between science and business.

Application note: CRISPR/Cas9 genome-edited cells express nanoBRET-donor that monitors protein interaction and trafficking

12 April 2018 | By BMG Labtech GmbH, Carl White (Molecular Endocrinology and Pharmacology), Ethan See (The University of Western Australia), Kevin Pfleger (Dimerix Limited)

In this application note, BMG Labtech discuss how the Bioluminescence resonance energy transfer (BRET) is a versatile tool to study interactions and trafficking in proteins.