Informatics

Scientists discover over 7,000 effective antibiotic combinations

3 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers discovered effective antibiotic combinations using four or five drugs, despite claims that combinations of three or more won't work...

Drug Target Review – Issue 3 2018

3 September 2018 | By Drug Target Review

In this issue: pharmacological targeting of mitochondrial dysfunction in Parkinson’s disease, the evolving role of three dimensional in-vitro cell culture techniques in drug discovery, and NGS: hunting mysterious ‘Dark Matter Genome’ towards rewriting the rules of genetic diseases.

Beckman Coulter, Inc.

AI system detects cancer tumours missed by conventional diagnostics

23 August 2018 | By Iqra Farooq (Drug Target Review)

Computer engineers have 'taught' a computer to identify tiny specs of lung cancer in CT scan images, often missed by radiologists...

SB Drug Discovery Ltd

Effective approach to optimising medicinal molecules

15 August 2018 | By Drug Target Review

Computational methods accelerates and automates the process of optimisation of candidate molecules before performing preclinical trials...

Recent advances in diagnostics and treatments – from small molecules to cellular therapies

14 August 2018 | By Bio-Techne

With recent advances in medicine, cellular therapies are one step closer to becoming a reality where re-programmed cells, tissues and organs can be used as therapeutic agents. This webinar discussed the journey of medical treatments from small molecule to cellular therapies...

Genetic model predicts risk for common deadly diseases

14 August 2018 | By Drug Target Review

Using data collected from the UK, the data suggests that up to 25 million people in the US may be at more than triple the risk of coronary artery disease...

Pushpanathan Muthuirulan

13 August 2018 | By

Research Associate, Harvard University

Computer simulations predict the spread of HIV

2 August 2018 | By Dr Zara Kassam (Drug Target Review)

Genetic signatures trace the origin of infection and its potential path through populations, allowing state health departments to track the disease...

Is acidity the weakness of cancer cells?

1 August 2018 | By Drug Target Review

Cancer cells proliferating in alkalinity should be more vulnerable in acidic environments, so decreasing the pH may result in decreased proliferation...

AI system designs drugs from scratch

1 August 2018 | By Dr Zara Kassam (Drug Target Review)

An artificial-intelligence approach created can teach itself to design new drug molecules from scratch and has the potential to dramatically accelerate the design of new drug candidates...

Novel antibiotics can be found on common weeds

31 July 2018 | By Drug Target Review

The team studied chemical compositions in detail and from one strain of bacteria several antibiotically active chemical substances were discovered...

New ligand binding site identified through computer simulations

30 July 2018 | By Drug Target Review

Many therapeutic compounds target GPCRs and so new ligand binding sites can help to design drugs more efficient at targeting GPCR...

Recessive disorder impairing eyesight has been discovered

24 July 2018 | By Drug Target Review

Blindness in children has been linked to a recessive genetic disorder caused by the MARK3 gene...