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Molecular biology

news

Largest multi-omics study of colorectal cancer to date

15 August 2024 | By Drug Target Review

Five distinct CRC prognostic subtypes were identified, which could revolutionise the way CRC is diagnosed and treated.

podcasts

Exploring the wonders of molecular biology

29 May 2024 | By Drug Target Review

In this episode, we explore our understanding of DNA and its implications for health outcomes. Additionally, we discuss the transition from DNA sequencing to actionable insights in medicine, contrasting genetics-driven drug discovery with traditional methods. Finally, we examine the evolving landscape of genetic technology and its potential impact on the…

news

Truncated version of the SMN2 gene could revolutionise drug discovery

15 March 2024 | By Drug Target Review

A condensed version of the SMN2 gene could improve discovery of potential therapies for spinal muscular atrophy and other conditions.

news

New insights into viral-related myocarditis

8 March 2024 | By Drug Target Review

Understanding heart changes at the molecular level during early infection with adenovirus could enable identification of those at higher risk of arrhythmia.

Chain of amino acid or bio molecules called protein - 3d illustration

news

How fusion proteins drive paediatric cancer

8 March 2024 | By Drug Target Review

Researchers discover that fusion proteins and a gene regulatory protein complex interact through disordered domains.

news

RAD51 prevents DNA re-replication

6 March 2024 | By Drug Target Review

Researchers find that the RAD51 protein prevents genomic duplications that could arise from reactivated origins.

article

Drug Target Review – Issue 4 2023

21 December 2023 | By

A new Drug Target Review issue is now ready to download! This issue features articles on CRISPR, personalised medicine and screening.

whitepaper

eBook: A Microscopy Guide For Spatial Biology

11 December 2023 | By Leica Microsystems

In this eBook, discover how to better understand tissue landscapes with different microscopy techniques including multiplex imaging.

article

Phages could help to tackle antimicrobial resistance

7 December 2023 | By Ellen Capon (Drug Target Review)

Researchers have found what triggers bacteria to start the CBASS immune response to counter infections by phages.

news

Potential biomarker found for inflammatory bowel disease

6 December 2023 | By Drug Target Review

A new approach called reverse metabolomics has discovered molecules that may serve as a biomarker or a therapeutic target for IBD.

whitepaper

Application note: Next-gen protein sequencing rapid ID of COVID variants

24 November 2023 | By Quantum-Si

Quantum-Si's Next-Generation Protein Sequencing technology on Platinum™, rapidly distinguishes SARS-CoV-2 variants based on amino acid sequence.

news

Potential of small molecule therapeutics for Barth syndrome

24 November 2023 | By Drug Target Review

Novel findings about the tafazzin gene offers a potential new target and drug candidate for Barth syndrome.

news

Genetic scar left in the genome of bacteria

6 October 2023 | By Drug Target Review

New study reveals how pneumonia cells become resistant to penicillin through evolutionary gateway.

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Molecular biology