Experimental antidepressant could also treat alcohol use disorder
A US pre-clinical study investigating the antidepressant: MAP4343, discovered it reduced alcohol intake in a mouse model of alcoholism.
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Measles virus can develop mutations that cause fatal SSPE
Japanese researchers find a new mechanism for how the measles virus can cause a rare but fatal neurological disorder: subacute sclerosing panencephalitis (SSPE).
AI tools aid the discovery of super tight-binding antibodies
An AI strategy developed by US scientists could accelerate the development of new antibody drugs.
Can ketamine act as an antidepressant?
Chronic pain often leads to depression, which US researchers have potentially solved using a mechanism involved with ketamine.
Discovery of CAFs’ origin gives new direction for pancreatic cancer
US researchers discovered a type of cell involved it pancreatic cancer and sheds light on the origin of cancer-associated fibroblasts (CAFs).
Hypothalamus versus hippocampus: changes in the synaptic plasticity
Japanese scientists analyse the associative synaptic plasticity in the supramammillary nucleus–dentate gyrus pathways.
Research reveals protein plaques associated with Alzheimer’s disease are stickier than thought
Scientists from Rice University are using fluorescence lifetime to shed new light on a peptide associated with Alzheimer’s disease.
Host-cell factors involved in COVID-19 infections may predict improved treatments
Researchers have found a potential therapeutic target less vulnerable to potential drug resistance and emerging COVID-19 variants of concern.
Combination of MRI and MSI uncover molecular secrets of Alzheimer’s
US researchers will use a unique combination of imaging techniques (MRI and MSI) to study Alzheimer’s disease on a scale that has never been done before.
The role immunological memory plays in fighting disease
US research about immunological memory may help development of potential vaccines or immunotherapies for cancer and various inflammatory diseases.
Different cardiac reactions to stress hormone in mouse study
US researchers use new imaging technique to see cardiac reactions to noradrenaline, the ‘fight or flight’ hormone.
Discovery of novel mechanism for MRSA virulence
US researchers revealed that MRSA has undergone repeated mutations in the sarZ gene, leading to increased severity of blood stream infections in mouse models.
Unexpected neuronal molecule makes prostate cancer more aggressive
US researchers discover a potential therapeutic avenue through the molecule NgR2, against an aggressive form of prostate cancer.
New treatment for MS using artificial nerve fibres
Danish researchers undertake a new project that aims to find new forms of treatment for diseases such as MS, which breaks down myelin and nerve fibres, by developing new, artificial nerve fibres
Researchers develop novel method to insert large DNA sequences more accurately in cells
The scientists say that the engineered CRISPR enzymes could overcome key limitations for eventual use to treat genetic diseases irrespective of a patient’s particular mutation.
