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National Research Council of Canada



Ion channels: Small molecules versus biologics – the quest for the ideal Nav1.7 inhibitor

21 September 2015 | By ,

Ion channels modulate and control many fundamental physiological processes in various tissues and alterations in their functions give rise to a wide range of pathophysiologies, which makes them important drug targets. Indeed, for decades, drugs modulating ion channel activity have been targeted by the pharmaceutical industry. Historically, however, developing drugs…