As the drug discovery industry takes on the complex disease states that plague our world, the need for more relevant and timely answers from cell-based assays has become a major challenge.
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An assay is an analytical procedure in laboratory medicine, pharmacology and molecular biology for measuring the activity of a target entity.
21 March 2018 | By Ben Jackson (Associate Director - Marketing - Bioline)
Next generation sequencing (NGS) has transformed biological research, invigorating the field of genomics, and has increased understanding of our genetic basis.
Application note: Simultaneous dual phosphoprotein target analysis with Alpha Terbium SureFire Ultra Multiplex
This application note discusses how the Alpha SureFire® Ultra™ Multiplex technology provides a phosphoprotein multiplexing detection platform that is truly homogeneous and high throughput.
19 March 2018 | By Anis H. Khimani (PerkinElmer)
Physiologically relevant screening models have become increasingly important in assay development and the screening of drug candidates.
19 March 2018 | By Drug Target Review
Declining R&D productivity is a key challenge in the pharmaceutical industry. To increase the success rate of candidate drugs entering the clinical phase, companies must address the early stages of drug discovery.
Predictiveness is one of the key factors for success in the drug discovery workflow. Many compounds fail at late stages due to lack of predictive data or the discovery of unwanted side effects.
14 March 2018 | By Drug Target Review
In this issue: how customised cell engineering advances immunotherapy, how insights into auto-immunity are providing new opportunities for immune-oncology, and advances in lab automation and robotics are accelerating the pace of antimicrobial therapy.
12 March 2018 | By Dr Zara Kassam (Drug Target Review)
Protein pathways that are closely linked to changes in both triglyceride and haemoglobin A1c levels in diabetic patients have been identified...
9 March 2018 | By Dr Zara Kassam (Drug Target Review)
Individuals who release low numbers of schistosome eggs in their faeces may now use the Helmintex method-- which uses a magnetic field to isolate eggs to detect infections...
8 March 2018 | By PerkinElmer
Case study detailing a simple, highly reproducible phenotypic screen to characterise human induced pluripotent stem cells...
Application Note: Alpha Terbium SureFire Ultra Multiplex: simultaneous dual phosphoprotein target analysis
8 March 2018 | By PerkinElmer
In this application note, PerkinElmer demonstrates the measurement of two phosphoprotein targets in a single sample using the Alpha Terbium SureFire Ultra kit combined with the AlphaLISA SureFire Ultra kit...
28 February 2018 | By Molecular Devices
Cellular imaging acquisition and analysis system at an affordable price point.
14 February 2018 | By Dr Zara Kassam (Drug Target Review)
NIH scientists have modified an assay to offer the possibility of improving early diagnosis of Parkinson’s disease and dementia with Lewy bodies...