Learn how to screen for cell viability with the CellTiter-Glo assay on the SpectraMax® iD5 Multi-Mode Microplate Reader.
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An assay is an analytical procedure in laboratory medicine, pharmacology and molecular biology for measuring the activity of a target entity.
Using absorbance microplate readers to streamline beer, wine and food safety analyses using industry-standard approved methods.
Get increased sensitivity for the detection of endotoxin in a fluorescence assay.
Therapeutic drugs based on biological materials (antibodies, hormones, cytokines, enzymes, fusion proteins) may have the ability to elicit an immune response in the host.
Pharmacokinetics (PK) refers to the movement of a drug through the body. The distribution, absorption, metabolism, and excretion of a drug are all important pharmacokinetic factors to be considered in the development of therapeutics.
Cell lysates can be prepared using a variety of methods including physical disruption, reagent-based lysis, or a combination.
Researchers in Australia and the US have launched the first open-source database detailing genetic variants that impact human health and disease.
MTT and Cell Cytotoxicity assay kits from Abcam can both be used to measure cell proliferation (viable cells) and cytotoxicity. The choice of which assay to use is mainly based on the desired workflow and time required to complete an assay.
Find out how to accelerate and improve selective single cell cloning with advanced microfluidic dispensing.
Learn how to quantitate a cellular protein sample with BCA protein assay kits on the SpectraMax® iD5 Multi-Mode Microplate Reader from Molecular Devices.
22 October 2019 | By Halo Labs
Aqueous solubility of small molecule compounds is an essential parameter during the hit-to-lead stage of drug discovery as well as lead optimization and formulation. Low solubility can result in misleading ADMET/DMPK analyses if some fraction of a compound precipitates. Watch on-demand to find out more!
Application note: Evaluate anti-inflammatory compounds using a multiparametric THP-1 cell-based assay
Macrophages originate from blood monocytes that leave the circulation and penetrate various tissues where they differentiate into macrophages. They are involved in the removal of pathogens and phagocytosis of dead cells. In addition, they initiate inflammation by releasing cytokines that activate vascular cells and facilitate macrophage adhesion to blood vessels…
A study that identified 12 novel compounds that may prove valuable against new drug targets for leishmaniasis and Chagas disease was not without complication. Here, we discuss the findings but also the challenges the researchers reported in their hit-to-lead study.
Automated fluorescence imaging and quantification of cell viability, with EVOS cell imaging system
High-throughput fluorescence imaging and analysis of spheroids - tips, tricks, and tools to efficiently grow, stain, image, and analyze 3D cell cultures