Bile acids and the microbiome: revolutionising disease approaches
Thousands of bile acids have been discovered, providing new insights into how microbes influence distant organ systems.
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Thousands of bile acids have been discovered, providing new insights into how microbes influence distant organ systems.
Tune in to this episode where we discuss the opportunities CRISPR/Cas technology offers to revolutionise drug discovery.
A new study provides more clarity about the immune events surrounding the onset of T1D, including a new mechanism that could be used for β-cell protection.
Researchers have discovered a new pathway which seems to be a significant contributor to the development of cardiovascular disease.
Single-cell RNA analysis provides an immunological explanation for the association between periodontitis and diabetes mellitus.
This guide provides technical background on concepts and techniques for use of Transcreener biochemical assays to measure drug-target residence times.
Researchers found that resolvinT4 restores protective macrophage biological activities in rheumatoid arthritis patients.
A deep learning model developed using circulating cell-free DNA outperformed traditional screening methods for gestational diabetes mellitus.
In this Q&A, Keith Murphy, CEO of Organovo, discusses how the shift from animal models to 3D human tissues can transform the preclinical space. Among his many insights, he details the limitations of animal models, how Organovo’s 3D human tissue models facilitate a deeper understanding of genetic expression within specific…
A new study has identified targets to refine diagnostic tests, track disease progression, and discover more effective therapies.
The new study suggests that this gene therapy method may combat ARVC in both early and more advanced stages of the condition.
The guide provides examples of how Transcreener allowed rapid assay development to enable screening for kinases in innate immune pathways.
22 January 2024 | By Drug Target Review, sponsored by Bio Rad Technologies
Join this webinar to learn how the challenges with using certain viral vectors in gene therapy has advanced the development of a new generation of precise vectors with sustainable effects. Our experts will outline the limitations of existing vectors and how these can be overcome using modified recombinant non-replicative herpes…
Join us for our monthly Women in STEM series where we showcase and celebrate the achievements of inspiring women in the field. We had the privilege of interviewing Dr Mrunal Jaywant, Vice President of R&D at USP India. At USP India, Dr Jaywant oversees the Compendial Development, the Synthetic Chemistry,…
Learn more about Euretos computational disease model and how it predicts many of the known drug targets for RA.