Scientists have created new nanoparticle-based materials that could be used to deliver gene therapies in an adaptable way.
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Drug delivery refers to approaches for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect.
Despite the promise of gene therapies, significant challenges have emerged in the field. Dr Carsten Brunn discusses the current obstacles and opportunities when developing gene therapies.
Scientists have developed an implant that releases insulin-secreting cells which has shown success at treating diabetes in mice.
Researchers have shown that inhalable nanobodies at ultra-low doses can effectively neutralise SARS-CoV-2 in hamsters.
Researchers have developed software that can design complex DNA nanodevices which could be used to deliver medicine while in the body.
A new COVID-19 vaccine could provide protection from severe infection from a range of coronaviruses, studies in pigs have shown.
Researchers have shown that an mRNA delivery system can be used to produce the BDNF protein in rats to protect neurons from ischemia.
A team has developed a lotus-root-shaped construct to deliver iPSC-derived pancreatic beta-cells to patients with type I diabetes mellitus.
A new delivery vector using platelets has shown success in pre-clinical trials at delivering photothermal particles and immunostimulators to tumours.
A team have shown that a tumour-suppressing and killing molecule delivered to the brain by stem cells has been successful in mice.
A team has used two viruses to administer specific tumour components in mice with cancer to stimulate their immune system.
A novel nanotherapy can decrease intestinal inflammation and shrink lesions in rodent models of Crohn's disease, a study has shown.
Treating only a few nerve cells with the hyper-interleukin-6 (hIL-6) gene therapy stimulated the regeneration of nerves.
Scientists have developed an inhaled treatment for asthma that prevents excess mucus from building up in mice.
Scientists report their phage-based inhaled vaccine delivery system elicited a robust antibody response in both mice and non-human primates.