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Mitochondria

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Brain organoids: investigating the progression of Huntington’s disease

5 September 2024 | By Drug Target Review

Researchers found that HD can impair early brain development through defects associated with mitochondrial dysfunction.

news

Mitochondrial depletion results in abnormal protein accumulation

22 April 2024 | By Drug Target Review

Researchers find the mechanism which may underly the onset and progression of age-related neurodegenerative diseases.

Mitochondrial disease Mitochondrial DNA 3D rendering

news

Improved gene editing method for mitochondrial genetic diseases

26 February 2024 | By Drug Target Review

Researchers have developed the world’s first animal model with A-to-G mtDNA edits achieved using engineered TALEDs.

news

Improving cancer treatment by exploiting mtDNA mutations

30 January 2024 | By Drug Target Review

For the first time, mitochondrial DNA mutations could be used with immunotherapy to increase the chances of successful treatments.

news

Mitochondria-targeting antibiotics reduce aging in C. elegans

27 November 2023 | By Drug Target Review

Treating C. elegans with inhibitors of small or large mitochondrial ribosomes extended their median lifespan.

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Recommended

Mitochondria

Brain organoids: investigating the progression of Huntington’s disease

Mitochondrial depletion results in abnormal protein accumulation

Improved gene editing method for mitochondrial genetic diseases

Improving cancer treatment by exploiting mtDNA mutations

Mitochondria-targeting antibiotics reduce aging in C. elegans