List view / Grid view
In this special December edition of Women in STEM, we are privileged to feature Dr Catherine Sheehan, a distinguished figure whose journey in the field of STEM has been marked by passion, resilience, and impactful contributions. We explore her experiences, challenges faced, and the transformative impact of her work in…
In this eBook, discover how to better understand tissue landscapes with different microscopy techniques including multiplex imaging.
A new approach called reverse metabolomics has discovered molecules that may serve as a biomarker or a therapeutic target for IBD.
Quantum-Si's Next-Generation Protein Sequencing technology on Platinum™, rapidly distinguishes SARS-CoV-2 variants based on amino acid sequence.
A study explores some key biological mechanisms that help explain the therapeutic effects of medicinal cannabis on inflammation and other disease states. Here, researchers from the European Molecular Biology Laboratory outline their investigations into the effect of tetrahydrocannabinol (THC) on the enzyme Autotaxin.
New study reveals how pneumonia cells become resistant to penicillin through evolutionary gateway.
A study out of Japan reveals diversity of protein structures and how they fold in nature, uncovering a myriad of protein topologies.
A US study has overcome a major obstacle in cell-free DNA (cfDNA) testing or liquid biopsy, offering promising advancements in disease diagnosis and monitoring.
Researchers from Canada develop a greater understanding about the molecular mechanisms for memory development in early childhood.
Japanese researchers have developed activatable Raman probes based on 9CN-rhodol, offering a promising tool for detecting multiple enzyme activities in heterogeneous biological tissues. This new molecular design strategy allows for highly specific and sensitive detection of enzyme activities, offering potential applications in disease diagnosis and biological research.
The new findings could pave the way to safer aspirin alternatives and might also have implications for improving cancer immunotherapies.
Matthew Lloyd from the University of Bath reveals the importance of the Z-factor and Z’-factor in high-throughput screening, and how they can be used to determine assay performance, perform quality control on the screen, and identify active compounds.
Sheraz Gul, Head of Assay Development and Drug Repurposing at the Fraunhofer Institute, discusses the importance of performing comprehensive multiplex spatial and temporal profiling of drugs in pre-clinical research to decrease the risk of potentially undesirable events in later clinical studies.
In an ongoing discovery programme, a chemical-creation platform is being revealed – based on cubic molecules – that could help breathe new life into tired drugs.
The activity of enzyme ATE1, as seen by US researchers, flags misfolded proteins for destruction and is enhanced by binding iron-sulphur clusters.
