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Inside AACR: DARPins take aim at hard-to-treat tumours
Amelie Croset of Molecular Partners breaks down the DARPin developments featured at AACR 2025 – from targeted radiopharmaceuticals to precision-engineered immune cell engagers.
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Non-small-cell lung cancers
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Activating c-Cbl gene causes immune system to attack cancer cells
Upregulation of the c-Cbl gene causes degradation of the immune checkpoint protein PD-1 and may provide a possible new avenue for cancer therapies, according to researchers.
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Reducing NOVA1 helps prevent tumour growth in lung cancer
Researchers have identified a gene that when inhibited, reduced human non-small cell lung cancer tumours from growing...
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NRF2 pathway provides new approach to cancer drug discovery
Scientists have developed a promising new strategy for the discovery of novel anti-cancer therapies for non-small-cell lung cancers...
