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squamous cell carcinoma

neck with surgical scar - removal of tumour

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Novel protein inhibitor improves immunotherapy in squamous cell carcinoma

22 July 2020 | By Hannah Balfour (Drug Target Review)

Researchers reveal a combination of PD1 immunotherapy and BMI1 protein inhibition eliminated cancer stem cells and prevented cancer recurrence in a mouse model.

x-ray of chest with lung cancer circled in red

news

Cancer mutation could be used to target CRISPR therapy

3 June 2020 | By Hannah Balfour (Drug Target Review)

Researchers reveal protospacer adjacent motif mutations (PAM sites) on the NRF2 gene of cancers could be used to guide CRISPR gene editing.

news

TAp63, miRNAs and AURKA: novel cutaneous squamous cell carcinoma drug targets

31 March 2020 | By Hannah Balfour (Drug Target Review)

The TAp63 tumour suppressor protein, two micro RNAs (miRNAs) and the AURKA gene can all suppress cutaneous squamous cell carcinoma (cuSCC) development, find researchers.

news

Np63a should be targeted in squamous cell carcinomas

19 September 2018 | By Iqra Farooq (Drug Target Review)

A team of researchers have identified that to target p63, both TGFB2 and RHOA tumour suppressor genes should be activated...

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Recommended

squamous cell carcinoma

Novel protein inhibitor improves immunotherapy in squamous cell carcinoma

Cancer mutation could be used to target CRISPR therapy

TAp63, miRNAs and AURKA: novel cutaneous squamous cell carcinoma drug targets

Np63a should be targeted in squamous cell carcinomas