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news

BenevolentAI hires new head of Cheminformatics from The Institute of Cancer Research

BenevolentAI announced today it has hired Dr Nathan Brown, as its new Head of Cheminformatics following the promotion of Mark Davies…

Cheminformatics

BenevolentAI announced today it has hired Dr Nathan Brown BSc (Hons) FRSC, as its new Head of Cheminformatics following the promotion of Mark Davies from Head of Cheminformatics to Vice President of Biomedical Informatics earlier in the year.  

Dr Brown joined the Institute of Cancer Research (ICR), London in 2007 where he founded and led the new In Silico Medicinal Chemistry Group which focused on medicinal chemistry research towards novel cancer treatments. Dr Brown holds a degree in computing from Robert Gordon University, Aberdeen and conducted his doctoral research in the field of Cheminformatics at the University of Sheffield.  Following his PhD he was awarded a Marie Curie Fellowship for two years working with Avantium in Amsterdam and subsequently one of the first to be awarded a prestigious Presidential Research Fellowship for three years, by Professor Mark Fishman, Global Head of Research at the Novartis Institutes for BioMedical Research.

With extensive experience as a software designer Dr Brown has developed many novel algorithms to maximise the impact of the experimental data generated in medicinal chemistry and cancer biology. Furthermore Dr Brown is a recent recipient of the Corwin Hansch Award for contributions to computational chemistry. 

 

Reserve your FREE place

 


Are low affinity or poor TCR yields slowing you down?

Explore how CHO expression of soluble TCRs and TCR affinity maturation workflows via phage, serving as essential building blocks for early-stage TCR-TCE candidate generation.

22 October 2025 | 16:00 PM BST | FREE Webinar

Join Jiansheng Wu, Ph.D. to explore two integrated strategies:

  • High-titer CHO-based expression of sTCRs (~100 mg/L), enabling scalable and high-throughput production
  • Optimized phage display affinity maturation, improving TCR binding by up to ~10,000-fold

Whether you’re starting a new TCR program or optimizing an existing platform, this session will offer actionable strategies to accelerate discovery and improve candidate quality.

Register Now – It’s Free!

 

Jackie Hunter, CEO of Benevolent Bío, the bioscience subsidiary of BenevolentAI, commented

“Nathan Brown is a recognised leader in the field of cheminformatics, molecular informatics and computational chemistry.  He has done exceptional work in the development of innovative anti-cancer therapies in an academic setting and his work is respected and well published.  We are delighted to have Nathan on board.”