Cells containing Meflin play a role in restraining the progression of pancreatic cancer and could lead to new therapies against the disease.
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A new platform has the potential to better understand what dictates the invasive behaviour of brain tumours.
A world-first compound that can keep cells alive and functioning in a healthy state could be revolutionary for medical emergencies.
The worldwide market for in vitro toxicology and toxicity testing is predicted to be worth $12.7 billion by the end of the forecast period.
Scientists in the US have developed a promising new CAR T-cell therapy that targets the BAFF-R protein, which has demonstrated superior cancer destruction to existing FDA-approved CAR-T therapies.
Researchers have shown that blocking a particular enzyme causes chemotherapy to become more effective against pancreatic cancers in pre-clinical studies.
Having worked in antibody research for over 20 years, Gary McLean has seen how the industry has progressed and understands the potential that antibodies have in the future of medicine. Nikki Withers hears how the focus has shifted from discovery to genetic sequence manipulation and how this can be applied…
Protein therapeutics are a major class of biopharmaceuticals and monoclonal antibodies (mAbs) rule this domain. In this article, Dr Nancy Lopez-Anton outlines the key technologies employed in this important therapeutic discovery area; how they have evolved and what obstacles must be navigated to ensure future success.
A new drug discovery strategy predicts the clinical actions of new compounds to promote desired clinical responses and avoid side effects.
A potential treatment for polycystic kidney disease has shown positive results in animal testing.
It is predicted that there will be 70 new monoclonal antibody (mAb) biotherapeutics available by 2020.
A study on how Polycombs regulate cellular identity could lead to alternative treatments for patients with drug-resistant cancer.
Monoclonal antibodies are used in a wide range of applications, such as basic research, biopharmaceutical development and in vitro diagnostics.