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Genome Editing

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Using 3D cell cultures to fight anti-cancer therapy resistance

13 December 2017 | By Dr Zara Kassam (Drug Target Review)

An international team of researchers have developed 3D cell cultures in which genes can be specifically modified to improve the use of targeted anti-cancer drugs...

news

CRISPR-dCas9 reveals surprising insight into breast cancer development

13 November 2017 | By Dr Zara Kassam (Drug Target Review)

Changing the epigenetic code of a single gene is enough to cause a healthy breast cell to become abnormal...

news

CRISPR engineered to edit single RNA letters

26 October 2017 | By Dr Zara Kassam (Drug Target Review)

New 'REPAIR' system edits RNA, rather than DNA, without permanently affecting the genome...

news

Alpha-1 antitrypsin deficiency shows promise in rare liver disease

20 October 2017 | By Dr Zara Kassam (Drug Target Review)

Nuclease-free gene editing has been found to correct mutated cells ...

news

CRISPR-engineered cancer model to test therapeutics

5 October 2017 | By Dr Zara Kassam (Drug Target Review)

A new technique for modelling leukaemia may aid drug discovery...

news

CRISPR-Cas9 used to systematically inactivate genes in colorectal cancer

28 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have used CRISPR-Cas9 to inactivate genes in human colorectal cancer cell lines -- one with normal KRAS gene and one with a mutant KRAS...

news

Genome editing reveals a role for OCT4 in human embryogenesis

21 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have used genome editing technology to reveal the role of a key gene in human embryos in the first few days of development...

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Recommended

Genome Editing

Using 3D cell cultures to fight anti-cancer therapy resistance

CRISPR-dCas9 reveals surprising insight into breast cancer development

CRISPR engineered to edit single RNA letters

Alpha-1 antitrypsin deficiency shows promise in rare liver disease

CRISPR-engineered cancer model to test therapeutics

CRISPR-Cas9 used to systematically inactivate genes in colorectal cancer

Genome editing reveals a role for OCT4 in human embryogenesis