Scientists have created new nanoparticle-based materials that could be used to deliver gene therapies in an adaptable way.
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A synthetically made glycopeptide biologic has shown promise as a treatment for obesity-related diseases in mice.
A team has characterised a key part of the peptide synthesis process, showing that only the main building block needs to be changed for re-engineering.
A team has demonstrated in mouse models that a self-assembling nanofibre material could limit the damage caused by cytokines in inflammatory diseases.
Although macrocyclic peptides make for promising pharmaceutical candidates, screening for lead peptides has proved difficult for scientists. In a new study, researchers at the Technion-Israel Institute of Technology addressed these challenges by developing a novel high-throughput screening assay for cyclic peptides with affinity to the ubiquitin protein. Drug Target Review’s…
A peptide that could treat multiple sclerosis caused no neurotoxicity or cardiotoxic effects in zebrafish, a study has shown.
A high-throughput screening assay for macrocyclic peptides with affinity to ubiquitin has been created by researchers.
A peptide administered to ferrets protected them from SARS-CoV-2 viral transmission when housed with infected ferrets.
A novel nanotherapy can decrease intestinal inflammation and shrink lesions in rodent models of Crohn's disease, a study has shown.
Researchers have synthesised peptides that function like a soluble chemokine receptor, blocking atherosclerosis in animal models.
New research has shown that 'hidden' lysis genes in bacteriophages could be used in the development of a new class of antibiotics.
A team has developed a new way to discover peptide therapeutics that inhibit HDAC enzymes and are effective against cancer.
Researchers report that their LEAPS COV-19 peptides significantly improved survival in a murine model of COVID-19.
A team fused the peptide somatostatin to a brain transport protein and found it treated memory loss associated with Alzheimer's in mice.