Mouse models show that activating a non-mutated form of the gene could lead to developing therapies for salivary gland cancer.
List view / Grid view
Ria Kakkad (Drug Target Review)
In primate models, researchers have successfully shown that developed AAVs can cross the blood-brain barrier, which keeps many drugs from getting into the brain.
Researchers have identified a protein that, when present in high amounts in breast cancer tumours, is an indicator of whether DNA-damaging therapies will work or not.
Drug Target Review’s Ria Kakkad recently travelled to Barcelona to attend PEGS Europe’s Protein and Antibody Engineering Summit. In this article, she shares her highlights from the event.
Researchers have developed a new method for comparing CAR T cells, each with slightly different molecular features, to determine which is most effective and long-lasting against cancer.
The research has shown in high-resolution detail how certain lipids interact with pacemaker ion channels to enhance their activity.
The study, involving mice, found that the neurotransmitter can act as a break to dopamine.
In their study, the researchers from the University of Maryland School of Medicine found that the Nsp6 SARS-CoV-2 protein causes heart damage.
A research team at the University of Exeter have found that the unexplored genomic control regions yield the key to finding causes of Congenital Hyperinsulinism.
Using DNA barcoding to track cancer cells through time, scientists have shown that the cells have diverse abilities to escape the immune system.
Researchers show how monkeypox mutations cause virus to replicate, spread faster.
The NPGPx protein is active in foetuses, but largely dormant and absent in diabetic adults.