angiogenesis

news

New DNA aptamer stabilises atherosclerosis plaques

30 August 2024 | By Drug Target Review

The nucleic acid drug, iSN04, could have applications for pathological angiogenesis involved in atherosclerosis, cancer, and retinopathy.

article

The challenges with antibody-based targeting of VEGF

12 February 2016 | By Sukmook Lee (Scripps Korea Antibody Institute)

Antibody-based targeting of vascular endothelial growth factor (VEGF) is a highly successful and widely-used clinical treatment for angiogenesis-related diseases. Currently, bevacizumab (Avastin; Genentech) and ranibizumab (Lucentis; Genentech/Roche) are the leading antibody drugs for targeting VEGF...

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angiogenesis

New DNA aptamer stabilises atherosclerosis plaques

The challenges with antibody-based targeting of VEGF