A study has revealed that the mitoNEET protein controls a metabolic and functional gateway on mitochondria, which could provide a drug target for cancer.
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The systematic successful treatment of cancer still eludes us and in an effort to refine this area of targeted medicine, Lauri Paasonen and colleagues explore the potential of using patient-derived cells (PDCs) for devising a personalised treatment strategy for solid tumours.
Having worked in antibody research for over 20 years, Gary McLean has seen how the industry has progressed and understands the potential that antibodies have in the future of medicine. Nikki Withers hears how the focus has shifted from discovery to genetic sequence manipulation and how this can be applied…
Researchers have discovered that B cells aid T cells in fighting cancer, which could be an area of development for immunotherapies.
Researchers have discovered an enzyme that is pivotal in deciding whether cells survive or die in inflammatory diseases, so provides a drug target.
A study on how Polycombs regulate cellular identity could lead to alternative treatments for patients with drug-resistant cancer.
Researchers discover that a non-coding region of the genome originates a key molecule for the proliferation of cancerous tumours.
A study has used CRISPR-Cas9 to treat obesity and type 2 diabetes symptoms in mice, highlighting the potential use in humans.
Scientists reveal the atomic structure and regulative mechanism of the metabolic enzyme transhydrogenase.
New discovery could lead to a new and highly potent immune-therapeutic drug for the eradication of cancers using natural killer cells.
Using new technology researchers have shown that sick mitochondria pollute the cells they are supposed to be supplying with power.
Researchers have discovered that MYC cancers use the cell’s machinery to make lipids and identified a lipid signature, which could be exploited in the development of new therapies.
The structure of a key receptor involved in tumour metastasis has been imaged in a study, providing opportunities to develop cancer treatments.