Leena Mol Thuruthippalli (Senior Product Manager – Protein & Cell Analysis at Thermo Fisher Scientific)

Expert view: Three-dimensional cell cultures as predictive tools in early drug discovery

6 December 2018 | By Leena Mol Thuruthippalli (Senior Product Manager – Protein & Cell Analysis at Thermo Fisher Scientific)

Three-dimensional cell cultures (spheroids, organoids) are becoming widely used as a new predictive tool in early drug discovery. The use of 3D cell cultures is believed to provide a more physiologically relevant response than monolayer (2D) cell cultures because they closely mimic the extracellular matrix and cell-cell interactions that occur…