Computational tool gets more out of multi-omics data
US researchers developed a next-generation computational tool called NetBID2 that can uncover difficult-to-identify proteins that drive biological processes contributing to cancer.
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Special omega-3 fatty acid lipid plays critical role in the ageing brain
Scientists from Singapore have sought to understand the role of Mfsd2a in brain cells, in transporting lysophosphatidylcholine (LPC), a lipid that contains an omega-3 fatty acid
Helper T cells may hold key to precision allergy treatment
US researchers have connected a rare T cell called Th9 with treating allergies, testing in mouse models with asthma.
Reviving T cells to tackle immunotherapy-resistant cancers
US researchers utilise a new approach to immunotherapy, using exhausted T cells that could help overcome treatment resistance in cancers.
Chances of eliminating HIV infection increased by dual gene-editing method
US researchers suggest that combing a dual gene-editing approach with antiretroviral drugs can eliminate HIV infections in animal models.
Scientists uncover new insights into rare childhood liver cancer
Researchers from the Netherlands have utilised organoids and the CRISPR-Cas9 "molecular scissor" system to better understand the features and biology of fibrolamellar carcinoma (FLC), a rare type of liver cancer that affects adolescents and young adults.
Blocking a microRNA may prevent age-related conditions
Conditions like chronic inflammation, muscle loss and bone loss have an elevated microRNA, US researchers attempted to block this in aged mice.
Researchers establish the first human respiratory organoid culture system
A team from the University of Hong Kong has developed the first human respiratory organoid culture system, using it to unveil a novel mechanism for the high transmissibility of the SARS-CoV-2 Omicron variant.
Study links nutrients, brain structure, cognition in healthy aging
US researchers found that nutrient intake, brain structure and cognitive function contribute to healthier brains in aging adults, by looking at correlating blood markers.
Genetics behind facial and skull changes in Down Syndrome mouse model
Progress in identifying the gene responsible for facial and skull changes in mouse model of Down Syndrome, made by UK researchers.
Rhythmic brain activity helps maintain temporary memories
US researchers have discovered that rhythmic brain activity organises the neuronal pathways that maintain short-term memories.
T cells show immunity to a variety of bacteria
Australian scientists explored a group of bacterial pathogens that share a protein sequence which is recognised by human T cells.
Organ-on-a-chip device aids the study of thrombosis without animal models
Scientists from the University of Birmingham have developed an organ-on-a-chip-model to better understand the mechanisms of deep vein thrombosis.
Innovative treatment targets blood clots without increased bleeding risk
Safer and more effective blood thinners could be on the way following a ground-breaking discovery by US researchers, that have designed a new compound to target blood clots.
Researchers develop Raman imaging probes for detecting enzyme activities
Japanese researchers have developed activatable Raman probes based on 9CN-rhodol, offering a promising tool for detecting multiple enzyme activities in heterogeneous biological tissues. This new molecular design strategy allows for highly specific and sensitive detection of enzyme activities, offering potential applications in disease diagnosis and biological research.
