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Nicola Burgess-Brown

 

Compound and fragment screening by native mass spectrometry

Native mass spectrometry has the potential to be a fast,…

14 June 2019 | By ,

Native mass spectrometry has the potential to be a fast, simple, highly sensitive and automatable technique for compound screening in drug design and discovery. In this article, Rod Chalk and Nicola Burgess-Brown discuss the key attributes of native mass spectrometry and reasons why it is not yet widely employed.

Screening In-Depth Focus 2019

This in-depth focus discusses screening and the uses of phenotypic…

7 June 2019 | By

This in-depth focus discusses screening and the uses of phenotypic profiling in drug discovery. Also examined is the role that CRISPR/Cas9 gene editing and native mass spectrometry play.

Mass Spectrometry In-Depth Focus 2015

In this Mass Spectrometry In-Depth Focus: Michelle M. Hill from…

3 December 2015 | By , , , ,

In this Mass Spectrometry In-Depth Focus: Michelle M. Hill from University of Queensland discusses Mass spectrometric and systems biology approaches in drug target discovery, and Nicola Burgess-Brown, Rod Chalk, Claire Strain-Damerell and Pravin Mahajan from the Structural Genomics Consortium look at analysing recombinant proteins by mass spectrometry...