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Prof Dr James Adjaye

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Urine-derived stem cells as innovative platform for drug testing and disease modelling

Kidneys are crucial for filtration of drugs and toxins and…

20 July 2018 | By , , , , , ,

Kidneys are crucial for filtration of drugs and toxins and their proper function is essential for overall health. Unfortunately, due to disease and improper function, kidney transplantation or dialysis are necessary for millions of patients annually all over the world.1,2

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Stem Cells In-Depth Focus 2018

In this issue: urine-derived stem cells offer an innovative platform…

31 May 2018 | By

In this issue: urine-derived stem cells offer an innovative platform for drug testing and disease modelling, a paradigm shift in translational stem cell research, and the role of biomaterials in stem cell-based regenerative medicine.

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Stem Cells In-Depth Focus 2017

Included in this Stem Cells In-Depth Focus: Translating discoveries into…

5 June 2017 | By

Included in this Stem Cells In-Depth Focus: Translating discoveries into therapies; The key to successful manufacturing of patient-specific cell therapies; Interview with Alessandro Prigione and James Adjaye...

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Strategies for identifying predictive biomarkers of non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD), a consequence of sedentary life…

17 March 2016 | By , , ,

Non-alcoholic fatty liver disease (NAFLD), a consequence of sedentary life styles and high fat diets, has an estimated prevalence of about 30% in western countries. It is associated with insulin resistance, obesity, glucose intolerance and drug toxicity. Additionally, polymorphisms within genes such as PNPLA3, TM6SF2, APOC3, NCAN and PPP1R3B correlate…

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The promise of induced pluripotent stem cells for liver disease, toxicology and drug discovery

We discuss the steps required for differentiating human pluripotent stem…

9 April 2015 | By , , ,

We discuss the steps required for differentiating human pluripotent stem cells into hepatocyte-like cells, and how long this process takes and the quality control measures needed...

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James Adjaye

Chair of Stem Cell Research and Regenerative Medicine, Heinrich Heine…

6 November 2013 | By

Chair of Stem Cell Research and Regenerative Medicine, Heinrich Heine University

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An interview with James Adjaye, Heinrich Heine University

Prof. Dr. James Adjaye, Chair of Stem Cell Research and…

28 October 2013 | By Prof. Dr. James Adjaye

Prof. Dr. James Adjaye, Chair of Stem Cell Research and Regenerative Medicine and Director of the Institute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University, talks to Drug Target Review about his research background, why he believes Drug Target Review will be a success and why he decided…