Taking a novel approach to antibiotic discovery, researchers at Rockefeller University have hit upon a promising solution to the problem of superbugs – a pervasive threat in hospitals the world over.
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Antibiotics are a type of antimicrobial drug used in the treatment and prevention of bacterial infections.
All mice infected with anthrax spores were completely protected after treatment with a pegylated enzyme known as PEG-CapD-CPS334C.
The new group of molecules can be chemically altered, showing potential for the development of effective antibiotics with few side effects.
Scientists targeted a mouse's own cells using a synthetic molecule called EEZE, presenting a novel way to treat pneumonia.
Scientists have used several machine learning models to predict bacterial gene exchange, which could reveal novel antibiotic targets.
The antimicrobial hygromycin A was shown to clear Lyme disease in mice, representing a promising therapeutic against the disease.
New dendritic hydrogels were tested against several infectious bacteria and could be used as an an antibiotic-free treatment in the future.
Researchers have created the first “living medicine” to treat antibiotic-resistant bacteria growing on the surfaces of medical implants.
Lipophosphonoxins may represent the next generation of antibiotics and can be delivered using a new type of dressing for skin wounds.
A new ex vivo model treated animal wounds with mesenchymal stromal cells (MSCs) and reduced MRSA infection, expanding therapeutic options for humans.
New research has explored the role of nasal bacteria to better develop intranasal vaccines for viruses such as COVID-19 and flu.
Researchers have used comparative metabologenomics to uncover what may be “silencing” bacteria to produce desirable compounds.
An experimental drug suggests that therapy for currently untreatable cases of cystic fibrosis is “clearly achievable”.
Researchers have developed a platform named FAST to produce antibiotics that specifically target just the bacteria of interest.
Scientists have discovered that manipulating residues enables precision during the antibiotic biosynthesis assembly line.