A study has revealed the structure of an enzyme that promotes cancer growth by mutating RNA, which could be used in the development of cancer treatments.
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Researchers in Australia and the US have launched the first open-source database detailing genetic variants that impact human health and disease.
Researchers have shown that histones are vital in silencing genes and that their position is inherited in new cells, providing insight into how cancer cells can become resistant to therapy.
Researchers have found a gene that is crucial for the calcification of cardiovascular vessels in mice, which could be a target for heart attacks and stroke.
Researchers have discovered a protein that is required for T cell biological processes; they have also demonstrated the mechanism behind the protein.
'Prime editing', a new CRISPR genome-editing approach, is capable of directly editing human cells in an accurate and efficient way.
Mouse blastocyst-like structures called blastoids have been developed by a team which could be used to study early developmental diseases.
Researchers in the US have successfully produced a mouse model with a human MAPT gene to enable more accurate research into Alzheimer’s therapy.
New research provides insights into how cancers can arise when DNA polymerase delta is not functioning properly.
Researchers in the US have devised a new way to clearly image proteins located in synapses, which they hope will faciliate future treatment for diseases associated with blocked gene expression.
A study has revealed that using DNA-like molecules to repair gene mutations in models could act as a successful therapy for patients.
CRISPR is the buzzword of the moment in the drug discovery industry – mainly due to its potential to correct disease-causing mutations. However, those using the technology need to be mindful that it is used responsibly, and possible risks are considered before use. Mark Behlke discusses the potential of CRISPR…
Whitepaper: Evaluating the impact of error rate on productivity and cost savings in synthetic DNA fragments
GeneArt High-Q Strings DNA Fragments versus other suppliers’ products.