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IgE protein may protect against skin cancer
The components of the immune system that trigger allergic reactions may also help protect the skin against cancer, suggest new findings...
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Drug Targets
A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
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Hunger hormones offer promising avenue for addiction treatment
Hormones that signal the body's state of hunger and fullness could be the key to new treatments for drug and alcohol addiction...
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Study pinpoints the ‘Big Bang’ of tau-induced Alzheimer’s neurodegeneration
Scientists in the U.S. have identified what they believe to be the genesis of Alzheimer's disease – the precise point at which a healthy tau protein becomes toxic but has not yet formed deadly tangles in the brain. The finding opens up numerous avenues for treatment research.
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New targets found to reduce blood vessel damage in diabetes
Researchers identify new treatment targets for diseases associated with endothelial cell senescence, or ageing, such as diabetes, cardiovascular disease and age-related disorders...
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Next-generation therapeutic helps immune cells detect, destroy cancer
Researchers have found that cancer cells evade destruction by macrophages in two ways...
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Progress toward improved Wilson’s disease drug
Researchers have conducted promising preclinical experiments on a compound that could be used to treat Wilson's disease...
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Experimental drug combined with radiation extends the survival of GBM
A new study has shown that an experimental drug known as AZ32 significantly extends the survival of glioblastoma multiforme, the most common and deadly form of brain cancer...
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Researchers reveal therapeutic target for Influenza A
Researchers show altering the molecular interactions between the flu virus and host genes stunts virus replication...
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Researchers uncover new target to stop cancer growth
Researchers have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes that stimulate tumour progression...
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Human immune ‘trigger’ map paves way for better treatments
A discovery about how human cells are 'triggered' to undergo an inflammatory type of cell death could have implications for treating cancer, stroke and tissue injury, and immune disorders...
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Mini-ecosystems developed to test a molecules therapeutic effect
Research scientists have solved a major problem in chemistry and drug development by using droplet-sized 'mini-ecosystems to quickly see if a molecule can function as a potential therapeutic...
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Application note: Real-time detection of Gs and Gi Signalling in living cells
Genetically-encoded biosensors from Montana Molecular allow for detection of GPCR signalling...
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Platypus venom inspires potential new diabetes treatments
A metabolic hormone found in the venom and gut of Australia’s iconic platypus will now be investigated for its potential to treat type 2 diabetes...
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LM11A-31 restores some bladder function after spinal cord injury
An experimental drug that blocks abnormal neural communication after spinal cord injury could one day be the key to improving quality of life by improving bladder function...
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HIV vaccine elicits antibodies in animals that neutralise dozens of HIV strains
NIH study results represent a major advance for structure-based HIV vaccine design...
