New research provides insights into how cancers can arise when DNA polymerase delta is not functioning properly.
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Enzymes are macromolecular biological catalysts. Enzymes accelerate, or catalyse, chemical reactions.
A team has discovered that fungi use the Diels-Alder reaction to assemble new compounds that have potential pharmaceutical uses.
Researchers have discovered an enzyme that is pivotal in deciding whether cells survive or die in inflammatory diseases, so provides a drug target.
A compound that promotes the rebuilding of the protective sheath around nerve cells damaged in multiple sclerosis has been developed.
Scientists reveal the atomic structure and regulative mechanism of the metabolic enzyme transhydrogenase.
New findings suggest a possible new treatment strategy for severe dengue disease using the tryptase inhibitor, nafamostat mesylate.
A gene associated with a rare balance disorder also regulates the behaviour of an enzyme that increases the risk for Alzheimer's disease.
A pharmaceutical target has been identified by Duke University that, when activated, can reverse bone degradation caused by osteoporosis.
Researchers have discovered that removing the enzyme, PHLPP1, improves outcomes in a mouse model of sepsis so could be a potential drug target.
Salk scientists discover a pair of enzymes that drive non-small-cell lung cancer by promoting inflammation which could inform the development of new therapies.
A new study has found a novel way to target an enzyme involved in cancer growth, which could inform therapeutics for the condition.
A new study may provide the basis for combating malignant leukemia stem cells.
A cellular pathway may reduce side effects and extend immunotherapy duration in patients with the most common form of liver cancer.
A research team have developed a new CRISPR platform called RESCUE (RNA Editing for Specific C to U Exchange).