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22 June 2016 | By Victoria White, Digital Content Producer
TB Alliance and Takeda are to explore hits generated from a high-throughput screening programme conducted to find novel compounds to treat tuberculosis...
14 June 2016 | By Charles River
This webinar reviews successful high throughput screening programs to provide an overview of the process from assay development to final data package...
11 April 2016 | By Victoria White, Digital Content Producer
New research could pave the way for a new generation of anti-diabetic drugs that are activated by the presence of either blue or ultra-violet light...
17 March 2016 | By BMG Labtech
BMG LABTECH has developed the new reference multi-mode microplate PHERAstar® FSX reader for HTS applications. This reader was specifically conceived for the fastest read times, the best sensitivity and unmatched flexibility in all plate formats up to 3456 wells...
16 March 2016 | By Victoria White
Researchers from NIST have shown that high-throughput screening can dramatically speed up the challenging task of antimicrobial discovery...
In the past two decades, several alternative, non-radiometric assay formats have been developed for the high-throughput screening (HTS) of target classes such as protein kinases, which were previously screened using radiometric assays. Radiometric screening (and the expertise to perform such HTS) has thus declined in recent years...
Neglected tropical diseases pose a significant threat to public health and affect nearly one billion people in tropical and sub-tropical regions throughout the world. There is a pressing need to identify new therapeutics for NTDs and many developed nations are participating in drug discovery efforts...
29 January 2016 | By SMi Group
SMi group reports: Doug Johnson, Research Fellow at Pfizer will be giving a keynote address on Day 1 at the SMi’s 15th annual Advances and Progress in Drug Design conference...
Progress in the understanding of disease mechanisms provides new opportunities to discover molecules that modulate disease. To capitalise on these opportunities, successful lead discovery strategies need to build on insights into how a cellular phenotype or a target contributes to disease biology. Recent advances in induced pluripotent stem cells (iPSCs),…
20 November 2015 | By Victoria White
The compound exchange represents a novel, open innovation model of collaboration between the two companies.
Undoubtedly, you will have noticed the increase in the number of publications utilising flow cytometry, heard it mentioned more in meetings and probably even been targeted by several companies trying to sell you their latest cytometer. The rapidly advancing technology behind the cytometer and an increase in applications that use…
19 August 2015 | By Victoria White
Scientists have developed a potentially better and more accurate high-throughput screening technique and have used it to identify 24 drug candidates...
High throughput screening (HTS) continues to be employed in drug discovery as the primary source of identifying chemical starting points for drug discovery and tool compounds for chemical biology, respectively. Although small molecule drug discovery efforts have focused largely upon enzyme, receptor and ion-channel targets, there has been an increase…
10 June 2015 | By Kenji Schorpp, Kamyar Hadian, Sheraz Gul, Horst Flotow
In this Screening In-Depth Focus, high throughput screening is the topic focused on by Kenji Schorpp and Kamyar Hadian, Institute of Molecular Toxicology and Pharmacology, and Sheraz Gul, Fraunhofer Institute for Molecular Biology and Applied Ecology. They discuss the importance of the technique in drug discovery today as well as…
From the beginning of time in the drug discovery world, the integration of disciplines has driven the identification of new lead molecules. Chemists, pharmacologists and biologists work together to understand a disease state and how to perturb that state back towards a normal healthy condition. However, in the early days…
