Researchers discover that a non-coding region of the genome originates a key molecule for the proliferation of cancerous tumours.
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Researchers have successfully created a multi-organ in vitro model to test toxicity and efficacy of drugs.
Researchers announce positive pre-clinical results for two sickle cell disease treatment strategies.
The importance of characterising chemical starting points of drugs using appropriate in vitro ADME-toxicity assays
Over the past 30 years, one strategy the pharmaceutical industry has adopted in the drug discovery process has been to “fail early, fail often”.1,2 As most molecules in the early stages of drug discovery will have sub-optimal characteristics, significant modification is necessary to improve their properties.
New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.
Learn how the continued development of CRISPR gene editing technologies opens fresh possibilities for in vivo model design.
Three-dimensional cell cultures (spheroids, organoids) are becoming widely used as a new predictive tool in early drug discovery. The use of 3D cell cultures is believed to provide a more physiologically relevant response than monolayer (2D) cell cultures because they closely mimic the extracellular matrix and cell-cell interactions that occur…
Reporter gene assays have greatly helped our understanding of gene regulation and signal transduction in vitro and in vivo.
Team of oncology experts expand data in Tumor Model Compendium and present strong portfolio at industry conferences...
6 November 2018 | By PerkinElmer
This webinar outlined the fundamentals of a design process where an experimental analytics data workflow is being integrated into a more seamlessly interactive platform...