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A new study has demonstrated for the first time that mutations that affect myosin motor activity result in slower cell movements in vivo.
Researchers discover that a non-coding region of the genome originates a key molecule for the proliferation of cancerous tumours.
Researchers have successfully created a multi-organ in vitro model to test toxicity and efficacy of drugs.
Researchers announce positive pre-clinical results for two sickle cell disease treatment strategies.
The importance of characterising chemical starting points of drugs using appropriate in vitro ADME-toxicity assays
Over the past 30 years, one strategy the pharmaceutical industry has adopted in the drug discovery process has been to “fail early, fail often”.1,2 As most molecules in the early stages of drug discovery will have sub-optimal characteristics, significant modification is necessary to improve their properties.
New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.
Learn how the continued development of CRISPR gene editing technologies opens fresh possibilities for in vivo model design.