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13 June 2016 | By Victoria White, Digital Content Producer
A small protein in the skin called Rac1 appears to link well-known environmental triggers of the disease with a genetic predisposition to the condition...
8 March 2016 | By Edward D. Zanders, PharmaGuide Ltd, Cambridge, UK
Here, Edward D. Zanders explains his motivation behind writing ‘Human Drug Targets a Compendium for Pharmaceutical Discovery’ - a collection of current and potential drug targets mapped to human genes curated by the HGNC...
17 June 2015 | By Victoria White
A new study suggests 15-PGDH shows promise as a drug target to help tissue regeneration, particularly after bone marrow transplantation and tissue injuries...
Preclinical drug target validation has the aim to increase confidence in a particular drug target. The process proves the initial hypothesis that a particular molecular target is key or even causative for pathogenic or symptomatic mechanisms in a disease. Several success factors seem to be of particular importance for the…
