Neuropathologic similarities between dolphins and humans suggest that the former could act as an effective model for the study of diseases such as Alzheimer’s. Professor Giovanni Di Guardo explains why dolphins could provide researchers with a new window into neurodegenerative conditons.
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A team of researchers in Singapore has studied the activity of a receptor protein to identify whether it’s a key player in the development of neuropathy for patients undergoing chemotherapy.
Results of an international collaboration show promise for the future of motor neurone disease treatment efforts, as protective gene is identified.
Researchers have discovered that neuronal necrosis occurs in Alzheimer's earlier than previously though and revealed the YAP protein as a potential target.
A research team has shown that a key difference between neurogenic and non-neurogenic tissues is cross-linking proteins causing stiffness, a discovery that could be used to create new brain injury therapies.
Researchers have revealed that the disruption of oligodendrocytes, which produce myelin, may be a cause of autism spectrum disorder, so presents a therapeutic target.
Researchers have screened thousands of drugs to discover that C1 effectively blocks the production of amyloid fibrils, so could be an effective therapeutic.
Researchers have conducted a genetic screen in mice to discover a family of genes that contributes to the development of Huntington's.
A key receptor has been examined for the first time at high resolution which could lead to better treatments for conditions such as type 2 diabetes.
A new study is the first to describe a novel pharmacological chaperone that is capable of preventing Alzheimer's disease in mice.
A new study into why neurons in the gut die and how the immune system protects them could lead to better treatments for IBS that work by boosting polyamine production.
A study has revealed a brain circuit in mice that suppresses the need to eat without a feeling of nausea, presenting a new strategy for diet drugs.
A new experimental drug was shown by researchers to restore natural brain rhythms in mouse models of Alzheimer’s and promote learning and memory.
Researchers have revealed that astrocytes contribute to reward signalling in the brains of mice, so could be a novel target to treat drug addiction.
Using brain scans, a study has shown that schizophrenia patients have lower levels of the protein SV2A in their brains which presents a drug target.