Researchers have created a new technology which enabled them to discover more about the causes of Huntington’s disease and which can be used to test drugs.
List view / Grid view
Filter the results
Medical screening is a strategy used to identify the possible presence of an as-yet-undiagnosed disease in individuals without signs or symptoms.
Currently, there is no licensed treatment to slow or stop the progression of Parkinson’s disease. However, a team at Sheffield University in the UK are currently working to identify compounds that target the dopaminergic brain cells affected by the disease. Nikki Withers speaks to Dr Heather Mortiboys to hear how…
Upstream bioprocessing is the epicentre of biologics development, wherein scientists piece together a series of carefully chosen processes with contributing components and parameters to enable the production of highly effective biotherapeutics. Unjulie Bhanot explains why an effective data management system is vital in this quest for the next big therapeutic.
Steven van Helden, Chief Technology Officer at Pivot Park Screening Centre (PPSC), relies on efficient microplate readers for effective hit discovery.
Researchers have discovered a particular protein that is required for enterovirus replication and survival, presenting a therapeutic target.
A new drug discovery strategy predicts the clinical actions of new compounds to promote desired clinical responses and avoid side effects.
Whitepaper: Evaluating the impact of error rate on productivity and cost savings in synthetic DNA fragments
GeneArt High-Q Strings DNA Fragments versus other suppliers’ products.
Application note: Cell line development: accelerating antibody discovery by monitoring titre and glycosylation with the Octet® platform
Cell line development typically includes the screening of thousands of clones to identify the few that are stable, grow as expected and produce high yields of the bioproduct.
Application note: Faster and more reliable quantification of oligonucleotide interaction with human serum albumin using MST
Antisense oligonucleotides are an emerging therapeutic option for treating diseases with known genetic origin.
A significant hurdle in optimising antibody therapeutics is the screening of successive rounds of large libraries of mutant variants in order to recognise the ideal candidate.
A team from MIT sequenced bacteria samples from the digestive system which can be accessed by researchers to use in the development of treatments.
This eBook highlights a selection of 3D cell model applications as well as Molecular Devices solutions for acquiring and visualizing quantitative data.
The British Journal of Pharmacology has recommended that all studies it publishes should address sex as an experimental variable.
A research team have found a signalling pathway which plays a critical role in the maturation of periodontal ligament, providing information for the development of dental treatments.
Scientists reveal the atomic structure and regulative mechanism of the metabolic enzyme transhydrogenase.