As the drug discovery industry takes on the complex disease states that plague our world, the need for more relevant and timely answers from cell-based assays has become a major challenge.
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Medical screening is a strategy used to identify the possible presence of an as-yet-undiagnosed disease in individuals without signs or symptoms.
Application note: Simultaneous dual phosphoprotein target analysis with Alpha Terbium SureFire Ultra Multiplex
This application note discusses how the Alpha SureFire® Ultra™ Multiplex technology provides a phosphoprotein multiplexing detection platform that is truly homogeneous and high throughput.
19 March 2018 | By Mark Wigglesworth (Director High-Throughput Screening - AstraZeneca)
Efficient microplate readers play an important role in effective hit molecule discovery. Mark Wigglesworth, of AstraZeneca, explains what he looks for in this technology.
High throughput flow cytometry for multifactorial evaluation of novel therapeutic candidates using an innovative in vitro immunooncology screening platform
19 March 2018 | By IntelliCyt Corporation
This recent webinar focused on the role of IntelliCyt’s iQue Screener PLUS platform as a high throughput suspension cell screening platform to facilitate simultaneous assessment of multiple parameters, while using minimal sample volumes.
19 March 2018 | By Drug Target Review
Declining R&D productivity is a key challenge in the pharmaceutical industry. To increase the success rate of candidate drugs entering the clinical phase, companies must address the early stages of drug discovery.
Predictiveness is one of the key factors for success in the drug discovery workflow. Many compounds fail at late stages due to lack of predictive data or the discovery of unwanted side effects.
14 March 2018 | By Drug Target Review
Researchers have showed how a common virus hijacks a host cell’s protein to help assemble new viruses before they are released.
8 March 2018 | By PerkinElmer
Case study detailing a simple, highly reproducible phenotypic screen to characterise human induced pluripotent stem cells...
Application Note: Alpha Terbium SureFire Ultra Multiplex: simultaneous dual phosphoprotein target analysis
8 March 2018 | By PerkinElmer
In this application note, PerkinElmer demonstrates the measurement of two phosphoprotein targets in a single sample using the Alpha Terbium SureFire Ultra kit combined with the AlphaLISA SureFire Ultra kit...
5 March 2018 | By Drug Target Review
A team of investigators has found that the mcr-1 drug resistance gene, which encodes resistance to a drug that is used as a last resort, has been found for the first time in Shigella flexneri.
1 March 2018 | By SMi Group
SMi’s 2nd Annual Pharmaceutical Microbiology West Coast Conference will be taking place in San Diego, USA on the 7th - 8th June 2018.
Application Note: Fluorescence Polarization based assay for rapid, precise, high-throughput measurement of IgG & Fc containing derivatives
9 February 2018 | By BMG Labtech GmbH
The accurate, rapid and high-throughput measurement of IgG is essential in the development and manufacture of most therapeutic antibodies...
6 February 2018 | By PerkinElmer
Operetta CLS is a high-content cell analysis system featuring a unique combination of technologies to deliver high speed, sensitivity, and resolution...
5 February 2018 | By Charles River Laboratories
Signs collaboration agreement with AstraZeneca to offer state-of-the-art technology to clients.
1 February 2018 | By PerkinElmer
This webinar discussed a screening assay that recapitulates the activation of ER stress sensor IRE1 and an assay to quantify cell migration phenotypes, as applied to cardiovascular target validation and drug discovery.