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Medical screening is a strategy used to identify the possible presence of an as-yet-undiagnosed disease in individuals without signs or symptoms.
20 February 2017 | By BMG Labtech GmbH
Due to their role in signal transmission from the outside to the inside of a cell, G-protein coupled receptors (GPCRs) are prominent drug targets.
Christian Andersson, Product Development Manager at Takara Bio discusses hiPS-derived beta cells, which offer an unprecedented opportunity for diabetes research to model human physiology and ‘diseases in a dish’. Christian looks into the potential for new discoveries for diabetes and other metabolic diseases...
Flow cytometry is a laser-based technology – a powerful tool for drug discovery and the screening process and can be used in all settings, including research, clinical, pharmaceutical and biotechnology. The increasing capabilities of flow cytometers make their incorporation into drug development and screening optimal...
Ligands are useful tools for studying how proteins work in cells and could lead to the development of new drugs.
Information on significant properties of pharmaceutical tablets, such as their mechanical strength and dissolution, can now be obtained without resorting to the conventional, time-consuming and destructive testing methods, according to a new study completed at the University of Eastern Finland.
21 December 2016 | By DiscoverX Corporation
Designed for lead optimisation and safety profiling, DiscoverX’s SAFETYscan in vitro pharmacological profiling services improve off-target liability testing...
21 December 2016 | By DiscoverX Corporation
Rapid Target Discovery, Validation, and Selectivity Determination...
In this Screening In-Depth Focus, scientists from the Assay Development and Screening Platform of Helmholtz Zentrum München provide an overview of different high-throughput screening (HTS)-applicable assay types that can be applied to drug discovery campaigns. Plus an interview with Lee Babiss, CEO of drug discovery firm X-Rx, on the benefits…
The covalent modification of proteins by the attachment of ubiquitin (ubiquitination) is best known for its function to label proteins for proteasomal degradation. However, ubiquitination also plays non-proteasomal roles during signal transduction, DNA repair and protein sorting...
1 December 2016 | By Charles River
This webinar details a successful new strategy to identify small molecule therapies to treat protein-destabilizing monogenic disorders...
21 October 2016 | By DiscoverX Corporation
Monitoring cellular drug penetration and drug-target interaction enables assessment of compound efficacy and confirmation of mode of action...
10 October 2016 | By Niamh Louise Marriott, Digital Content Producer
Flexible plates therefore enable better image quality without increased compression force. One can also reduce the compression force and the pain...
4 October 2016 | By Cisbio
HTRF® cellular phospho-/total protein assays provide precise, sensitive measurement of endogeneous levels of phosphorylated and non phophorylated proteins able to be achieved in an endogenous cellular environment...
4 October 2016 | By Cisbio Bioassays
A line of high quality products have been developed, addressing biomarkers to meet the needs of multiple therapeutic areas such as inflammation, oncology, metabolic disease or CNS...
