product
PathHunter® MAX Panel Screening & Profiling Services
21 December 2016 | By DiscoverX Corporation
Rapid Target Discovery, Validation, and Selectivity Determination...
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Screening
Medical screening is a strategy used to identify the possible presence of an as-yet-undiagnosed disease in individuals without signs or symptoms.
article
Screening In-Depth Focus 2016
In this Screening In-Depth Focus, scientists from the Assay Development and Screening Platform of Helmholtz Zentrum München provide an overview of different high-throughput screening (HTS)-applicable assay types that can be applied to drug discovery campaigns. Plus an interview with Lee Babiss, CEO of drug discovery firm X-Rx, on the benefits…
article
HTS assays for the identification of small-molecule inhibitors of deubiquitinating enzymes
The covalent modification of proteins by the attachment of ubiquitin (ubiquitination) is best known for its function to label proteins for proteasomal degradation. However, ubiquitination also plays non-proteasomal roles during signal transduction, DNA repair and protein sorting...
webinar
New strategy to identify small molecule therapies
1 December 2016 | By Charles River
This webinar details a successful new strategy to identify small molecule therapies to treat protein-destabilizing monogenic disorders...
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DiscoverX In Vitro Pharmacology Services – Simplify Your Drug Discovery Workflow
21 October 2016 | By DiscoverX Corporation
Monitoring cellular drug penetration and drug-target interaction enables assessment of compound efficacy and confirmation of mode of action...
news
How breast cancer screening could be better and less painful
10 October 2016 | By Niamh Louise Marriott, Digital Content Producer
Flexible plates therefore enable better image quality without increased compression force. One can also reduce the compression force and the pain...
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Cisbio Bioassays Cell signaling phospho-assays
4 October 2016 | By Cisbio
HTRF® cellular phospho-/total protein assays provide precise, sensitive measurement of endogeneous levels of phosphorylated and non phophorylated proteins able to be achieved in an endogenous cellular environment...
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Cisbio Bioassays Biomarkers & cytokines – quantify intracellular and released proteins
4 October 2016 | By Cisbio Bioassays
A line of high quality products have been developed, addressing biomarkers to meet the needs of multiple therapeutic areas such as inflammation, oncology, metabolic disease or CNS...
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Cisbio Bioassays GPCR – Kits and reagents to address the whole GPCR activation pathway
3 October 2016 | By Cisbio Bioassays
Cisbio Bioassays has supported GPCR investigation for many years regularly creating cutting edge assays and technologies suited to receptor characterization, compound screening and lead optimization...
webinar
Use of IntelliCyt’s iQue Screener for high-throughput screening of small molecules, CRISPRs and stem cells
29 September 2016 | By Intellicyt
This webinar highlights the use of the iQue Screener for high-throughput screening of stem cells, small molecules and CRISPR functional screening, presented by David Sykes, M.D., Ph.D., Researcher from Massachusetts General Hospital and Thibault Jonckheere, CEO and Séverine Giltaire, Senior Scientist from ImmunXperts...
whitepaper
Poster note: Target discovery program in systemic sclerosis
Novel candidate drug targets for systemic scleroderma were identified using RNAi in phenotypic assays in scleroderma patient-derived fibroblasts...
article
A picture is worth a thousand endpoints: high-content imaging in drug discovery
Over the past few years several factors in the drug discovery industry have come together to drive an increased interest and subsequent surge in the use of high-content imaging. These include the high costs of attrition in the clinic due to lack of efficacy; increased hurdles and rising costs to…
article
Zebrafish early-life stages as neurological screening and detection tools
Unforeseen efficacy and safety-related issues with drugs continue to be a major cause of their attrition, despite significant efforts that are expended to eliminate them prior to initiating clinical trials...
product
Bio-Rad Bio-Plex Multiplex Immunoassay System
4 August 2016 | By Bio-Rad Laboratories
The Bio-Plex System offers high-performance readers, industry-leading software, and sensitive assays in ready-to-use or custom configurations, enabling you to obtain high-quality data from limited samples...
