Video: Bioprocess systems for perfusion process development at small and bench scale
We present cell retention technologies suitable for small and bench scale bioprocessing.
Perfusion cell culture processes help saving lab space, increasing volumetric productivity, achieving more consistent product quality, and improving production of less stable proteins. Experimentation at small and bench scale is crucial for the cost-efficient development of bioprocesses, which then can be transferred to larger production volumes.
In this webinar we present cell retention technologies suitable for small and bench scale bioprocessing. We show a case study of an ATF-based CHO cell perfusion process at a working volume of 1 L.
Key Learning Objectives:
- Connection of an ATF-2 cell retention device with Eppendorf bioprocess systems
- Bioprocess system technical requirements and configurations
- Analysis of process performance: Cell growth, metabolite concentrations, and product formation
- Other cell retention technologies, including packed-bed bioreactors and microcarrier spin filters
Duration (optional): 1 hour
Speakers: Amanda Suttle, Bioprocess Research Scientist at Eppendorf North America