Antibodies In-Depth Focus 2018
In this In-Depth Focus, Stefan R. Schmidt discusses the current status and future perspectives of monoclonal antibodies and Tony Edge explains why the determination of aggregate is critical in the formation of monoclonal antibodies.
In this In-Depth Focus:
- Monoclonal antibody discovery: current status and future perspectives
Since the first description of how to generate monoclonal antibodies was published in the 1970s, this field of research has grown tremendously. Currently, more than 70 full-length antibodies or fragments are approved by the major regulatory agencies globally. Looking back, a lot has changed since this historic discovery.
- Aggregate formation for monoclonal antibodies
Workflows are generated around the analysis of large protein-derived therapeutics. The use of different analytical techniques is necessary to support drug development and testing, and thus increase generation of these new therapies. One of the areas that is most critical to this process is the determination of aggregates.
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