Stem Cell In-Depth Focus 2019
This in-depth focus looks at the modification of stem cells to facilitate their efficient delivery to tumours, highlighting the new development of pluripotent stem cells.
Included in this In-Depth Focus:
- Stem-cell technologies in immunotherapy
In recent years scientists have developed many therapeutic molecules – such as bifunctional multi-targeting antibodies, fusion proteins and oncolytic viruses – and different types of stem cells are being modified to facilitate their efficient delivery to tumours, illustrating the great potential of engineered therapeutic stem cells. In this article, Aparajita Dubey, Associate Scientific Manager at Biocon biologics Limited, outlines the exciting developments that are taking place with immunotherapies and demonstrates how stem-cell technologies are proliferating the paradigm shift in how we tackle cancer treatment.
- Using stem cells to study the effects of cannabis on neuronal development
Thanks to new developments with induced pluripotent stem cells enabling generation of human neurons, scientists can more precisely analyse the effects that chemicals have on human cells. Trisha Rao, Montreal Neurological Institute, and Thomas Durcan, McGill University, expand on their research into the effects of cannabis on neuronal development and implications of its legalisation in Canada.