DNA nanostructures for drug delivery remain a technical challenge
13 May 2019 | By Drug Target Review
Many studies indicating that DNA nanostructures can enter cells more readily than simple DNA strands are 'flawed'.
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McGill University
Drug candidate offers hope of vocal improvement for ADNP syndrome
16 November 2018 | By Drug Target Review
Scientists have uncovered a promising drug candidate that appears to normalise the vocal communication mechanism deficiencies experienced in genetic disorder ADNP.
AI algorithm accurately predicts Alzheimer’s disease onset
5 October 2018 | By Drug Target Review
Scientists have developed an algorithm that can more accurately predict cognitive decline that leads to Alzheimer’s disease. Early preventive measures may help delay and even halt the disease’s onset.
ATP1A3 gene mutations associated with infantile forms of schizophrenia
21 June 2018 | By Dr Zara Kassam (Drug Target Review)
Scientists have identified novel genes associated with a specific form of schizophrenia the discovery will aid diagnosis and development of treatments...
Manipulating calnexin could lead to new MS treatments
13 March 2018 | By Dr Zara Kassam (Drug Target Review)
Researchers identify the overabundance of a specific protein in the brain of people who have MS...
Scientists discover new epigenetic cause of cblC that shifts rare disease paradigm
1 February 2018 | By Drug Target Review
Researchers in France and Canada have discovered an epigenetic alteration of a vitamin B12 gene – MMACHC – that has significant implications for our understanding of cblC and other rare diseases.
Artificial intelligence predicts dementia before onset of symptoms
23 August 2017 | By Dr Zara Kassam (Drug Target Review)
Scientists have used artificial intelligence techniques and big data to develop an algorithm capable of recognising the signatures of dementia two years before its onset, using a single amyloid PET scan...
How the anthrax toxin forms a deadly “conveyer belt”
28 September 2016 | By Niamh Louise Marriott, Digital Content Producer
During anthrax infections, the bacterium Bacillus anthracis secretes a toxin consisting of two related enzymes named lethal factor and edema factor...
Scientists find evidence linking Parkinson’s to autoimmune disease
27 June 2016 | By Victoria White, Digital Content Producer
Scientists have discovered that two genes associated with Parkinson's disease, known as PINK1 and Parkin, are key regulators of the immune system...
LDC and McGill enter translational drug discovery partnership
7 June 2016 | By Victoria White, Digital Content Producer
LDC and McGill University are to work together to identify tools to help develop novel endoplasmic reticulum related diseases therapies...
Brain cells that play a crucial role in appetite identified
13 May 2016 | By Victoria White, Digital Content Producer
Scientists have identified cells, NG2-glia, that play a crucial role in appetite and weight gain - a discovery that could lead to anti-obesity treatments...
USP19 inhibition protects against muscle wasting
15 September 2015 | By Victoria White
Researchers have discovered a new gene, USP19, involved in the muscle wasting syndrome cachexia that could be a good target for drug development...
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