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Five developments in oncology targets
Drug Target Review explores some of the newest oncologic drug targets, including those for glioblastoma, lung cancer and breast cancer.
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McGill University
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Effective analgesics are ‘some way away’ due to bias in pain research, says researcher
A review of pain research suggests it is biased towards males, despite most chronic pain sufferers being female, resulting in ineffective analgesics.
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Researchers reveal structure of mega-enzymes from bacteria and fungi
Researchers have uncovered the structure of nonribosomal peptide synthetases (NRPSs), an important ingredient in drug production.
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Research focus should remain on high quality studies during COVID-19 pandemic, say scientists
Exceptions to high quality research should not be made simply because of the COVID-19 pandemic, argue scientists in a new commentary.
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The latest developments in diabetes drug discovery
Several new advances have been made in the field of drug discovery for diabetes – here, three of the most recent have been rounded up.
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Study identifies virulence factors of Leishmania
Researchers have discovered the mechanism behind the spread of Leishmania, indicating a potential drug target.
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Stem Cell In-Depth Focus 2019
This in-depth focus looks at the modification of stem cells to facilitate their efficient delivery to tumours, highlighting the new development of pluripotent stem cells.
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DNA nanostructures for drug delivery remain a technical challenge
Many studies indicating that DNA nanostructures can enter cells more readily than simple DNA strands are 'flawed'.
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Drug candidate offers hope of vocal improvement for ADNP syndrome
Scientists have uncovered a promising drug candidate that appears to normalise the vocal communication mechanism deficiencies experienced in genetic disorder ADNP.
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AI algorithm accurately predicts Alzheimer’s disease onset
Scientists have developed an algorithm that can more accurately predict cognitive decline that leads to Alzheimer’s disease. Early preventive measures may help delay and even halt the disease’s onset.
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ATP1A3 gene mutations associated with infantile forms of schizophrenia
Scientists have identified novel genes associated with a specific form of schizophrenia the discovery will aid diagnosis and development of treatments...
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Manipulating calnexin could lead to new MS treatments
Researchers identify the overabundance of a specific protein in the brain of people who have MS...
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Scientists discover new epigenetic cause of cblC that shifts rare disease paradigm
Researchers in France and Canada have discovered an epigenetic alteration of a vitamin B12 gene – MMACHC – that has significant implications for our understanding of cblC and other rare diseases.
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Artificial intelligence predicts dementia before onset of symptoms
Scientists have used artificial intelligence techniques and big data to develop an algorithm capable of recognising the signatures of dementia two years before its onset, using a single amyloid PET scan...
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How the anthrax toxin forms a deadly “conveyer belt”
28 September 2016 | By Niamh Louise Marriott, Digital Content Producer
During anthrax infections, the bacterium Bacillus anthracis secretes a toxin consisting of two related enzymes named lethal factor and edema factor...