New research has revealed that club cells secret anti-immunosuppressive factors in tumours, potentially revolutionising cancer therapies.
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Anna Begley (Drug Target Review)
This article delves into research at the University of California Los Angeles, US, where stem-cell derived brain organoids that can mimic electrical activity have been developed.
A breaking discovery has revealed the gene HSD3B1 that regulates the production of sex hormones is linked to atopic dermatitis (AD).
The decreased expression of PTEN in mouse models was found to make rhabdomyosarcoma tumours more aggressive, highlighting new treatment approaches.
Researchers have established an organoid biobank to search for genes that are essential for the spreading of SARS-CoV-2 infection.
A new ex vivo model treated animal wounds with mesenchymal stromal cells (MSCs) and reduced MRSA infection, expanding therapeutic options for humans.
Scientists have discovered drug targets in the neural circuits that encode memories, paving the way for the treatment of brain disorders.
MEPs have requested that the EU adopts new plans to phase out the use of animals in scientific research and testing, focusing on alternatives instead.
New technology system of drug-based markers for the selection or counter-selection of genes may advance genetic screening methods.
Researchers discovered that glioblastoma cells rely on biotin distribution for growth, leading to possible future drug combinations.
New genomic study reveals that the microbiome could predict rheumatoid arthritis prognosis, potentially advancing treatments.
A novel gene therapy has fully corrected whole-body alterations in a rat model, paving the way for Morquio A therapies.
Researchers have identified a spider-like antibacterial mechanism by immune cells that could inspire Staphylococcus aureus treatments.
An NIH team have built a cellular map of chronic multiple sclerosis (MS) lesions to identify cells that drive inflammation and potential therapies.