Researchers have developed a novel peptide with a prolonged half-life that has demonstrated success in rhesus monkeys and mice for inhibiting HIV infections.
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Victoria Rees (Drug Target Review)
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Researchers have created two new cellular models that can be used in the study of ocular diseases and drug testing.
A study has demonstrated that inducing brain vessel pulsations helps to clear substances from the brains of mice, so could be used to stop amyloid-β build up in the development of Alzheimer’s.
The ICR has revealed that during drug discovery, researchers should not use general search engines and vendor catalogue information to decide on their use of chemical probes.
A study has demonstrated how mutations in early colon cancer prevail and grow into malignancies, using fluorescent imaging.
Researchers have found that, in rainbow trout models, phages on mucosal surfaces infect pathogenic bacteria, providing protection.
A study has demonstrated that a novel vaccine design for pancreatic cancer has been successful in mice, doubling survival time.
Scientists have shown that the mutated CUL3 gene, which is involved in the cell’s clearance of proteins, plays a role in the development of autism and schizophrenia in mice.
Researchers have found that MAIT immune cells respond rapidly to group A streptococcal infection, causing inflammation and toxic shock, which presents a therapeutic target.
A compound that has antimicrobial properties has been found by researchers, which could be used to combat drug-resistant infections.
A study has discovered that the PKM2 protein plays a role in regulating immune cells and blocking this could be a potential treatment for inflammatory diseases.