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Electrical channels in retina could play role in degenerative diseases
Researchers have discovered electrical channels important in sensory cell renewal which could be studied further to develop therapies for retinal diseases.
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Victoria Rees (Drug Target Review)
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Fruit fly model for studying uric acid diseases developed
Researchers have created a fruit fly model to investigate uric acid-related diseases such as diabetes to aid in drug development.
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Researchers identify potential drug target for depression in primates
A study has discovered a molecule key in neuronal growth that could be used as a drug target to treat anxiety-related diseases.
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Nanotechnology platform could improve stem cell transplantation
A team has developed a technique for identifying pluripotent stem cells that could help research on transplantation medicine.
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Process for rejuvenating aged rat brain stem cells discovered
A research team has developed a method for regenerating old brain stem cells from rat models, which could be used to treat age-related brain diseases.
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‘Ubiquitin clipping’ proteomics technique could be used as novel treatment
A new technique called ‘ubiquitin clipping’ has been created which could aid proteomics research and the development of new drugs for ubiquitination.
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Molecule identified as key in pancreatic cancer metastasis
New findings show that the environment for pancreatic cancers plays a role in its metastasis, revealing a new potential drug target.
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Four cell types discovered in glioblastoma tumours
A new study has revealed that glioblastomas contain four different types of cell which the researchers say should be treated separately.
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Five newest developments for imaging in drug research
Imaging methods are used by scientists to identify therapeutic targets and improve drug efficacy. This article lists five of the latest developments for imaging techniques.
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Experimental compound could be used to treat pancreatic cancer
Using a compound called PTC596 in combination with other drugs, researchers effectively treated pancreatic cancer in mice.
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Interferon pathway could provide drug target for cancers
A study has found that signals from interferons can be blocked, allowing the immune system to attack tumours which provides a potential target.
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Allergy-driving cells identified as potential drug targets
Researchers have discovered a subtype of immune cells that contribute to allergic reactions and anaphylaxis, providing a drug target.
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Study reveals cancer cell fuelling mechanism
Researchers have identified the process behind cancer cell energy production, providing a drug target for treatments to inhibit growth.
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Cancer cell nutrient pathway mechanism discovered
Researchers have discovered the mechanism behind a gateway into cells for glutamine, illuminating potential ways to prevent cancer cells from getting nutrients.
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Motor neuron disease electrical signalling pathways mapped
A study has used EEG to investigate the neuron networks that act abnormally in the condition, providing a significant step in the search for treatments.