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Scientists identify new way to target leukaemia cells
Researchers have found they can make leukaemia cells vulnerable by dislodging leukaemia stem cells from a tumour-promoting niche.
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Victoria Rees (Drug Target Review)
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Analysis of mouse neuroinflammation samples aided by flow cytometry
A new study has highlighted the advantages of using flow cytometry for the analysis of neuroimmune cell populations from mouse models.
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New imaging method reveals glycan vaccine targets on HIV molecules
Using cryo-electron microscopy and site-specific mass spectrometry, researchers have mapped the glycans that shield HIV from the immune system.
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Flow cytometry market to exhibit CAGR of 12 percent
A new report has said that by 2023, the flow cytometry market will be worth $8.88 billion, partly due to an increase in stem cell research.
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Novel vaccine protects mice from lung, bowel and pancreatic cancer
By targeting the mutated KRAS gene, researchers have developed an experimental vaccine that protected mice against a range of cancers.
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Mini lung organoids reveal early SARS-CoV-2 infection process
Using lung organoids, researchers have shown that 48 hours after SARS-CoV-2 infection, the innate immune response began.
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CBD could treat inflammation caused by COVID-19, study shows
Researchers have found that CBD reduces inflammation in the lungs of COVID-19 mouse models by increasing levels of the apelin peptide.
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First draft sequence of human proteome released
Researchers have mapped 90 percent of the human proteome, which could inform the development of new medicines.
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Assay to reveal anti-tumour T-cell cytotoxicity via flow cytometry developed
A simple co-culture assay that can assess anti-tumour T-cell cytotoxicity via luminescence and flow cytometry has been created.
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Study reveals roles of antibodies in SARS-CoV-2 disease severity
Researchers have found that the level of antibodies in the serum of SARS-CoV-2 patients correlated with disease severity.
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Over 200 molecules and genes linked to COVID-19 severity
A team has identified 219 molecules and genes that influence the severity of COVID-19 in patients, providing information that could aid the development of therapeutics.
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siRNA nanomedicine shows promise Alzheimer’s treatment in mice
Researchers have shown that an siRNA nanomedicine can target BACE1 in a mouse model of Alzheimer's, restoring cognitive capacity.
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COVID-19 vaccines should not be affected by SARS-CoV-2 mutations, researchers say
A common SARS-CoV-2 mutation known as D614G should not impact on the efficacy of COVID-19 vaccines, a study has shown.
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Nobel Prize in Chemistry awarded to scientists who discovered CRISPR-Cas9
Emmanuelle Charpentier and Jennifer Doudna have been given the 2020 Nobel Prize in Chemistry for their discovery and development of CRISPR-Cas9 genome editing.
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High doses of favipiravir combat SARS-CoV-2 in hamsters
A team showed that high doses of favipiravir can treat hamsters infected with SARS-CoV-2, whereas hydroxychloroquine has no effect.