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Biomarker in blood could determine severity of COVID-19
A study has shown that patients with severe COVID-19 have significantly elevated levels of M-MDSCs in their blood compared with healthy individuals.
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Victoria Rees (Drug Target Review)
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Novel compound named BC1618 could serve as new diabetes drug
Researchers have identified a new compound that improved responses to insulin and treated diabetes in obese mouse models.
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Two novel molecules to potentially combat asthma discovered
Researchers have discovered that giving L-tyrosine and PCS to mice prevents lung inflammation and an allergic asthma response.
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Researchers develop novel way to identify new cancer drugs
A team has developed a new way to discover peptide therapeutics that inhibit HDAC enzymes and be effective against cancer.
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Rhesus macaques with SARS-CoV-2 develop promising immune response
A study has shown that the immune response of rhesus macaques with SARS-CoV-2 could be reproduced with a vaccine.
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Researchers uncover insights into pioneer transcription factors
A research team has discovered how proteins called pioneer transcription factors turn on vital genes in cells.
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SARS-CoV-2 triggers antibodies from previous coronavirus infections
A new study has shown that previous coronavirus infection may contribute to the immune response of patients infected with SARS-CoV-2.
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Study defines small-cell lung cancer subtypes and therapeutic vulnerabilities
Researchers have identified four unique subtypes of small-cell lung cancer (SCLC) following the characterisation of cell types.
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Scientists develop potential ‘smart’ stem cells made from human fat
Using a new compound mixture, researchers have created adaptive and regenerative stem cells from human fat cells.
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Novel IRF4 inhibitor shows promise as myeloma treatment in mice
An antisense oligonucleotide has been developed by researchers to inhibit IRF4 as a potential strategy to treat multiple myeloma.
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A novel CAR T-cell therapy to treat lymphomas
A new form of CAR T-cell therapy has shown promise in mice models to treat blood cancers; this article delves into the development behind the therapy.
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CBD shown to kill Gram-negative bacteria in pre-clinical studies
Researchers have shown that CBD can kill Gram-negative bacteria, which could lead to the first new class of antibiotics for resistant bacteria in 60 years.
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Researchers discover mechanism behind severe cases of G6PD deficiency
Researchers have revealed how the most severe cases of G6PD deficiency occur, which could help scientists design new drugs for the disease.
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Scientists identify nutrient that helps prevent bacterial infection
Scientists have identified a potential alternative to antibiotics, a nutrient named taurine that helps the microbiome kill invading bacteria.
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New method for rapid development of vaccines for pre-clinical tests
Using synthetic chemistry, researchers have fused hydrophobic adjuvants with water-soluble proteins to create a new type of vaccine.