The researchers revealed the mechanism by which signalling becomes dysfunctional in upper motor neuron (UMN) diseases, such as amyotrophic lateral sclerosis (ALS).
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Amyotrophic Lateral Sclerosis (ALS)
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Drug Target Review discusses how NETSseq, a novel profiling technology, is bringing new insights to neurodegenerative and psychiatric diseases.
Researchers have shown that, when treated with L-serine, a non-human primate model of ALS had fewer pathologies associated with the disease.
Results of an international collaboration show promise for the future of motor neurone disease treatment efforts, as protective gene is identified.
Scientists using a new motor neuron disease (MND) model have shown astrocytes may protect neurons from toxic TDP-43 protein aggregates in the early stages of disease.
Researchers have developed a screening system and identified a set of compounds that protect neuronal mitochondria in mice.
Disrupted protein homeostasis from PI31 inactivation may initiate the process of neurodegeneration seen in Alzheimer’s, ALS and other similar diseases, says new research.
A potential target for ALS has been revealed by a study which found the Fos-B gene encouraged axonal branching.
A study has used EEG to investigate the neuron networks that act abnormally in the condition, providing a significant step in the search for treatments.
Arizona company claims their products can treat Lyme disease, diabetes, Parkinson’s disease and more, but have not been approved for any use.
Researchers have made discoveries about the formation of cellular components called membraneless organelles and the key role these organelles play in cells...
PARP inhibitors show promise in preventing toxic accumulations of brain disease proteins in Penn research study...
A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS).