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Researchers reverse obesity in mice using CRISPR-Cas9
A study has used CRISPR-Cas9 to treat obesity and type 2 diabetes symptoms in mice, highlighting the potential use in humans.
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Could gene mutation offer new treatment options for cardiometabolic disease?
Researchers in the states have discovered a particular gene mutation that slows down sugar metabolism in the gut, indicating future treatment options for individuals with cardiometabolic and sugar-associated diseases.
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NLRP12 protein promotes healthy gut bacteria to curb obesity
Scientists have discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet...
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Blocking RNA-silencing protein Ago2 shows promise for obesity prevention
Researchers are hopeful of finding a means to inhibit obesity and its associated health problems after a study in which they blocked an RNA-silencing protein in the livers of mice, preventing obesity and diabetic conditions.
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Aortic plaques may contribute to liver disease progression
Aortic atherosclerotic plaque inflammation may contribute to the progression of non-alcoholic fatty liver disease to liver fibrosis...
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KLF14 gene may increase risk of type 2 diabetes
Scientists have identified a gene that in women is linked to the creation and location of new fat cells and therefore is thought to contribute to the risk of type 2 diabetes...
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FGF21 gene variant found to lower body fat
Researchers have found that a gene that makes humans eat more sugar can also lower body fat...
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I-BET-762 may stop cancer-causing gene in its tracks
Scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer...
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3-D imaging of fat reveals potential targets for new obesity treatments
A new report reveals the inner workings of fat tissue in mice and identifies potential targets for new drugs to treat and prevent obesity and diabetes...
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Anti-obesity drug shrinks fat without suppressing appetite
Researchers have discovered a drug that has been shown to selectively shrink excess fat by increasing fat cell metabolism...
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Researchers use smartphone data in global study of physical activity
Researchers at Stanford University in Palo Alto, California, have tracked physical activity by population for more than 100 countries.
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Major new appetite regulator successfully manipulated in mice
A new study has found a link between certain brain receptors and obesity, giving a possible new drug target for appetite regulation.
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Obesity behind surge in kidney cancers
Kidney cancer rates have increased by 40% over the last 10 years in the UK, and the rise is expected to continue. An estimated 20,000 kidney cancer cases have been caused by obesity over the last decade in England, according to new figures from Cancer Research UK.
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Obesity can reprogram muscle stem cells
Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden.
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Flu vaccines fail to protect obese mice
8 August 2016 | By St. Jude Children’s Research Hospital
Using vaccines prepared from killed viruses, the scientists targeted an influenza A H1N1 seasonal flu strain, finding that obese mice are not protected against influenza infections through vaccines, raising concerns about vaccine response in obese humans, who are known to be at an increased risk for severe flu...