Explaining uveal melanoma’s resistance to conventional immunotherapies
Researchers have developed a new tool called ‘Uveal Melanoma Immunogenic Score’ to predict which patients will respond to adoptive therapy.
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Researchers have developed a new tool called ‘Uveal Melanoma Immunogenic Score’ to predict which patients will respond to adoptive therapy.
The new findings could lead to new therapeutics and a method to diagnose pancreatic cancer earlier, improving its prognosis.
Researchers have designed the first small molecule drug targeting K-Ras GD12, which could improve pancreatic cancer outcomes.
The first complete control map for any protein has been made for KRAS, and four potential drug targets have been discovered.
Dr Catherine Pickering, CEO of iOnctura, the clinical stage biopharmaceutical company delivering pioneering cancer treatments to patients with unmet medical needs, is at the forefront of cancer drug discovery. Dr Pickering and her team identify targets that have crucial roles in multiple tumour survival pathways, collaborate with world-renowned scientists and…
A novel treatment approach using DON molecule starves tumours of essential nutrient, significantly slowing tumour growth.
US scientists have used mouse models of pancreatic cancer to identify genes used by tumour cells to grow uncontrollably.
The finding is an critical first step towards classifying lesions on the pancreas that are at highest risk of becoming cancerous, enabling their removal before they start to spread.
US researchers discovered a type of cell involved it pancreatic cancer and sheds light on the origin of cancer-associated fibroblasts (CAFs).
This article outlines three innovative studies that use nanotechnology to deliver a new immunotherapy approach towards cancers.
A new implant that combines internal radiation and chemotherapy dissolved tumours in mice across multiple models.
In pre-clinical studies, the University of Florida has identified two drugs that reverse ADM, a process that precedes pancreatic cancer.
Researchers have revealed the immune landscape and microbiome of pancreatic cysts as they progress to pancreatic cancer, providing targets for immunotherapy.
Researchers analysed the expression of long non-coding RNAs in samples from patients and tumour cell lines, identifying a group of genes with augmented expression in pancreatic cancer.
A new study has shown that it is possible to reverse key process that allows pancreatic cancer cells to grow and spread around the body.