A promising new treatment strategy for hepatoblastoma
A combination therapy of vincristine, irinotecan and panobinostat, tested in high-risk, relapsed or refractory HB spheroids, decreased tumour marker levels.
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A combination therapy of vincristine, irinotecan and panobinostat, tested in high-risk, relapsed or refractory HB spheroids, decreased tumour marker levels.
By studying the molecular cell states within transplanted paediatric hearts, researchers have unlocked new treatment strategies.
A new strategy enables researchers to be more precise in the control of gene expression of a therapeutic protein.
A new discovery about the dynamic structure of norovirus particles has implications for vaccine development.
Researchers have discovered a molecule that binds to a cancer cell protein, stopping growth of breast and ovarian tumours.
Researchers designed the first magnetoelectric material that precisely stimulates neurons to treat nerve damage.
US researchers innovate cancer diagnostics using Kinase Inhibitor Pulldown Assay, or KIPA, to search for proteins they could target to control tumour growth.
US researchers uncover a new drug that reduces the ability of bacteria to develop antibiotic resistance, prolonging the antibiotic effectiveness.
US researchers have uncovered a novel method using a tool used to visualise ion channels in mechanosensory neurons.
US researchers have uncovered a potential target for treating breast cancer that is resistant to endocrine therapies because of a specific gene mutation.
The researchers explored the possibility of using the probiotic bacteria Lactobacillus reuteri as a novel oral drug delivery platform to treat rheumatoid arthritis in an animal model.
The researchers found that the protein Grb10 promotes leptin activity in the brain, opening the possibility of developing Grb10-based new approaches to treat obesity.
A US researcher studied 3D structures of brain cells and connections, revealing new role for oligodendrocyte precursor cells (OPCs), in mice.
Drug Target Review’s Ria Kakkad recently visited ELRIG and the British Pharmacological Society’s conference on New Modalities in Pharmacology and Drug Discovery which took place in London, UK. This article shares some of the key takeaways from the event.
Researchers have found that genetically and pharmacologically restoring the normal activity of the brain circuit improved anorexia, opening the possibility of developing a treatment strategy for affected individuals in the future.