Researchers have revealed that the protein ALYREF promotes the effects of the neuroblastoma gene, MYCN, making it a target.
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Children's Cancer Institute
The drug combination of difluoromethylornithine and AMXT 1501 has shown success against Diffuse Intrinsic Pontine Glioma in animal models.
A study has discovered that reducing expression of a key gene in neuroblastoma tumourigenesis is an important drug target for the condition.
Researchers have uncovered a crucial link between polyamines and MYCN, revealing that the polyamine pathway is entirely regulated by the MYCN oncogene...