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Scientists have linked rare mutations in SPNS1 to a previously unknown lipid recycling pathway in lysosomes, revealing how faulty fat processing can trigger muscle and liver disease.
Scientists in Singapore have discovered that gut support cells – known as telocytes – use neuron-like extensions to deliver signals directly to intestinal stem cells. This could lead to new treatments for diseases such as inflammatory bowel disease and colon cancer.
Nearly a billion people are affected by chronic organ scarring, yet treatments remain limited. Now, Duke-NUS researchers have compiled a scientific ‘handbook’ of immune cell insights that could fast-track breakthroughs in fibrosis therapy.
New insights into the role of SUMOylation in the brain could lead to new targeted therapies for neurodegenerative conditions.
Understanding the signalling pathway controlling neural stem cell reactivation could offer a strategy for using existing drugs to treat neurodevelopmental disorders.
Scientists from Singapore have sought to understand the role of Mfsd2a in brain cells, in transporting lysophosphatidylcholine (LPC), a lipid that contains an omega-3 fatty acid
A new study has suggested that asymptomatic individuals with COVID-19 mount an efficient T-cell response that protects the host.
A new signalling protein discovery could lead to drug-based therapies to treat hyperparathyroidism.
