German Center for Neurodegenerative Diseases (DZNE)

news

Utilising CAAR T cells to treat antibody-caused brain disease

6 November 2023 | By Drug Target Review

Researchers have engineered CAAR T cells to destroy harmful antibodies, improving NMDA receptor encephalitis treatment.

AUTOIMMUNE DISEASE. TEXT ON A WOODEN BAR on a blue background. Medical concept.

news

Scientists capture first images of an autoantibody attacking a neuron receptor

15 July 2022 | By Ria Kakkad (Drug Target Review)

Researchers for the first time have captured images of an autoantibody bound to a nerve cell surface receptor, revealing the physical mechanism behind a neurological autoimmune disease.

neurons in purple surrounded by yellow protein aggregates - idea of Alzheimer's disease

news

Antibodies stimulate microglia to degrade Alzheimer’s amyloid plaques

11 March 2020 | By Hannah Balfour (Drug Target Review)

A novel antibody has been shown to stimulate microglia to degrade amyloid plaques in a murine model of Alzheimer’s disease.

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Recommended

German Center for Neurodegenerative Diseases (DZNE)

Utilising CAAR T cells to treat antibody-caused brain disease

Scientists capture first images of an autoantibody attacking a neuron receptor

Antibodies stimulate microglia to degrade Alzheimer’s amyloid plaques