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Insilico Medicine

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Insilico and Qilu partner to create generative AI cardiometabolic drugs

29 January 2026 | By Drug Target Review

Insilico Medicine and Qilu Pharmaceutical Group are expanding their existing R&D collaboration to apply generative AI to cardiometabolic drug discovery.

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Insilico secures $888million Servier partnership for AI oncology

6 January 2026 | By Drug Target Review

Insilico Medicine and Servier have announced a multi-year collaboration to accelerate the discovery of new cancer therapies, using artificial intelligence to tackle challenging oncology targets and shorten early-stage drug development timelines.

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AI-powered CKD drug ISM4808 licensed for kidney disease therapy

15 December 2025 | By Drug Target Review

Insilico Medicine has partnered with TaiGen Biotechnology to exclusively license its AI-designed PHD inhibitor, ISM4808, for the treatment of CKD-related anaemia in Greater China.

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AI powers discovery of new CBLB inhibitor ISM3830

2 December 2025 | By Drug Target Review

Insilico Medicine has announced ISM3830, an AI-designed CBLB inhibitor that has demonstrated promising preclinical results.

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Scientists spotlight lung disease as fast-track model for ageing drugs

9 September 2025 | By Drug Target Review

Researchers have identified idiopathic pulmonary fibrosis (IPF) as a powerful model for exploring treatments that target the biology of ageing.

Doctor working office research studying heart disease illness, using modern computer technology display assistance artificial intelligence AI, healthcare medical staff in hospital clinic office

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AI targets protein linked to most human cancers

4 June 2025 | By Drug Target Review

Scientists have used AI to design a molecule that disrupts a key protein interaction driving up to 70 percent of cancers - once thought impossible to drug.

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First AI-designed drug, Rentosertib, officially named by USAN

14 March 2025 | By Drug Target Review

Insilico Medicine’s AI-designed drug for idiopathic pulmonary fibrosis (IPF), Rentosertib, has been granted an official name by USAN. This is the first drug where both the target and compound were discovered using generative AI, marking a major milestone in AI-driven drug development.

Scientists are using laptop to research cancer or covid treatment in lab. medical human body analysis technology. Scientific research with intelligent AI system innovation Develop an antiviral vaccine

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AI-designed CDK12/13 inhibitors target resistant cancers

5 March 2025 | By Drug Target Review

Insilico Medicine’s AI-designed CDK12/13 inhibitors show promise against treatment-resistant cancers. Find out how this breakthrough could reshape cancer therapy.

news

FDA greenlights AI-developed drug targeting solid tumors

4 December 2024 | By Drug Target Review

Insilico Medicine’s AI-designed drug ISM5939 has received FDA IND clearance for treating solid tumours. By targeting ENPP1, it enhances anti-tumour immunity and is set to begin Phase I trials soon.

whitepaper

Beyond the lab: artificial intelligence

28 February 2024 | By Drug Target Review

Amidst the transformative era of AI in drug discovery, this report focuses on recent advancements, notably the development of highly accurate drug target models, and how AI is revolutionising precision in identifying drug targets.

article

Game-changing pan-TEAD inhibitor for solid tumours

12 June 2023 | By Fraser Owen (Drug Target Review)

Insilico Medicine has announced the nomination of ISM6331 as a potential best-in-class pan-TEAD inhibitor for the treatment of advanced solid tumours.

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Using virtual screening to identify coronavirus treatments

10 March 2020 | By Victoria Rees (Drug Target Review)

Drug Target Review rounds up the latest updates on research into coronavirus treatments, focusing on virtual screening to find therapies for COVID-19.

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AI designed, synthesised and validated new drug in 46 days

2 September 2019 | By Victoria Rees (Drug Target Review)

Researchers have developed a new AI system which was able to discover and then successfully test several new compounds within 46 days.

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