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Model to study oculocutaneous albinism eye conditions developed
The first patient-derived stem cell model to research eye conditions related to oculocutaneous albinism (OCA) has been created.
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Fraser Owen (Drug Target Review)
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Organoid system simulates human liver-islet axis in diabetes
Scientists have developed a multi-organoid system from stem cells that can replicate the liver-islet axis in type 2 diabetes.
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Delivering gene therapies to the brain to treat Alzheimer’s
Dr Ronald G Crystal, Professor and Chairman of the Department of Genetic Medicine, Weill Cornell Medical College, spoke to Drug Target Review’s Fraser Owen about his research into Alzheimer’s disease and why gene therapies represent a promising area of research for neurodegenerative conditions.
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Five of the latest developments in 3D bioprinting
Drug Target Review brings you five of the most recent developments in three-dimensional (3D) bioprinting.
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New tool reveals DNA structures that influence disease
Researchers have created an algorithm that locates and analyses DNA structures which are linked to the development of certain diseases.
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Specific gene implicated in cardiovascular calcification
Researchers have found a gene that is crucial for the calcification of cardiovascular vessels in mice, which could be a target for heart attacks and stroke.
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New CRISPR technique could alter the way we look at brain diseases
Researchers may have fundamentally altered the way scientists study brain diseases with new CRISPR technology.
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Process for rejuvenating aged rat brain stem cells discovered
A research team has developed a method for regenerating old brain stem cells from rat models, which could be used to treat age-related brain diseases.
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Macrophages identified as cause of endometriotic pain
Researchers have discovered that macrophages are a key cause for pain in women with endometriosis so could be a treatment target for the condition.
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New technique developed to expand multimodal single cell analysis
A new technique, called ECCITE-seq, has been developed to allow researchers to perform high-throughput measurements of multiple modalities of information from single cells.
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Cancer vaccine shows promising results in Lynch syndrome
Vaccination with as few as four tumour antigens generated antigen-specific responses, reduced intestinal tumours, and improved survival in a mouse model of Lynch syndrome...
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Protein marker in response to brain cancer therapy
An extremely powerful MRI scanner was used to image proteins in the brain of cancer patients and has shown that protein content correlates with treatment...
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Digital 3D brain cell atlas released
The Blue Brain 3D atlas could be the future of analysing all cells in the brain, with high quality, high resolution images that can navigate the brain...