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P53 could be key to therapies for salivary gland cancer
Mouse models show that activating a non-mutated form of the gene could lead to developing therapies for salivary gland cancer.
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University of Michigan Rogel Cancer Center
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Binding site of drug compound and tumour suppressor protein revealed
Using cyro-electron microscopy, researchers have imaged the binding site between a molecule and the tumour suppressor protein PP2A, enabling optimisation of the drug compound.
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The loss of CDK12 pinpoints to a new sub-type of prostate cancer
Tumours with alterations in the CDK12 gene were more responsive to immunotherapy, suggesting precision medicine approach...
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Immune processes offer insights into triple-negative breast cancer
Researchers have discovered the process that allows immune suppressor cells to develop, suggesting a potential new way to bolster immunotherapy treatment...