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Assays

 

An assay is an analytical procedure in laboratory medicine, pharmacology and molecular biology for measuring the activity of a target entity.

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ProteinSimple Milo

12 January 2017 | By ProteinSimple

Single-Cell Western system capable of analysing protein expression in ~1,000 single-cells in parallel to unlock heterogeneity...

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Screening In-Depth Focus 2016

11 December 2016 | By , , ,

In this Screening In-Depth Focus, scientists from the Assay Development and Screening Platform of Helmholtz Zentrum München provide an overview of different high-throughput screening (HTS)-applicable assay types that can be applied to drug discovery campaigns. Plus an interview with Lee Babiss, CEO of drug discovery firm X-Rx, on the benefits…

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HTS assays for the identification of small-molecule inhibitors of deubiquitinating enzymes

4 December 2016 | By , ,

The covalent modification of proteins by the attachment of ubiquitin (ubiquitination) is best known for its function to label proteins for proteasomal degradation. However, ubiquitination also plays non-proteasomal roles during signal transduction, DNA repair and protein sorting...